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Table 4 The differences in insulin sensitivity and beta-cell function between the insulin- and diet-treated women with GDM from the university hospital

From: Differences in pregnancy outcomes and characteristics between insulin- and diet-treated women with gestational diabetes

 

Diet N = 196(73.0 %)

Insulin N = 73(27.0 %)

P value

Adjusted p value

ISSI-2 index mean

1.7 ± 0.5

1.3 ± 0.5

<0.0001

<0.0001

Matsuda index median

2.9 (1.9–3.7)

2.3 (1.4–3.3)

0.019

0.206

1/HOMA-IR median

0.02 (0.01–0.03)

0.01 (0.01–0.02)

<0.0001

0.027

  1. GDM: gestational diabetes; ISSI-2: insulin secretion sensitivity index during pregnancy; Matsuda: insulin sensitivity index of Matsuda during pregnancy; 1/HOMA-IR: the reciprocal of the homeostasis model assessment of insulin resistance during pregnancy. The p-values are adjusted for age, BMI, excessive weight gain, ethnicity and multi-parity, P-values in bold are significant values