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Table 3 Unadjusted and adjusted Odds Ratios (OR) and corresponding 95 % confidence intervals (CI) for delivery related outcomes for women treated with donated oocytes (Index group) compared to women treated with traditional IVF (Control group B)

From: Adverse obstetric outcomes in pregnancies resulting from oocyte donation: a retrospective cohort case study in Sweden

Outcome

Index group n/N(%)

Control group B, n/N(%)

Crude OR (95 % CI)

Adjusted OR (95 % CI)

Normal delivery

21/76(27.6 %)***

39/63(61.9 %)

0.25 (0.12–0.53)***

0.29 (0.13–0.65)**

Instrumental deliverya

13/58 (22.4 %)

12/53(22.6 %)

0.90(0.35–2.33)

0.86 (0.29–2.55)

Caesarean Section (CS)

42/76(55.3 %)***

12/63 (19 %)

6.01 (2.65–13.59)***

5.20 (2.21–12.22)***

Non emergency CS

18/76 (23.7 %)

10/63(15.9 %)

2.21 (0.91–5.40)

1.82 (0.71–4.66)

Emergency CSa

24/58(41.4 %)***

2/53 (3.8 %)

16.96 (3.68–78.24)***

15.98 (3.27–78.23)**

Induction of labora

33/58(56.9 %)***

12/53(22.6 %)

3.19 (1.35–7.56)***

2.80 (1.10–7.08)*

Uterine Inertia, primary-secondarya

13/58 (22.4 %)*

4/53 (7.5 %)

3.24 (0.94–11.17)

3.67 (0.92–14.66)

Hypertensive disorders of pregnancyf

12/76 (15.8 %)

6/63 (9.5 %)

2.08 (0.73–5.93)

1.66 (0.54–5.08)

Pregnancy-Induced Hypertension

2/76 (2.6 %)

0

–

–

Preeclampsia

10/76 (13.2 %)

6/63 (9.5 %)

1.44 (0.49–4.21)

1.39 (0.44–4.42)

Fetal distressa

16/58 (27.6 %)*

5/53 (9.4 %)

3.22 (1.04–9.99)*

2.86 (0.83–9.86)

Very preterm birth (<32 weeks)

3/76 (3.9 %)

0

–

–

Preterm birth (<37 weeks)

13/76 (17.1 %)*

3/63 (4.8 %)

3.94 (1.04–14.88)*

3.45 (0.88–13.62)b

Maternal Hospitalization post partum

    

≥2 days

73/75 (97.3 %)*

54/63(85.7 %)

10.87 (1.34–90.91)*

5.26 (0.55–50.35)c

≥3 days

59/75(78.7 %)**

35/63(55.6 %)

3.03 (1.39–6.58)**

1.74 (0.70–4.34)c

Post-partum hemorrhage

12/76 (15.8 %)

6/63 (6.5 %)

1.47 (0.49–4.42)

3.67(1.03–13.03) d*

Retained placentae

8/34 (23.5 %)

4/51 (7.8 %)

3.83 (1.01–14.53)*

2.98 (0.73–12.18)

  1. All outcomes are adjusted for maternal age (<35, ≥35 years), BMI (<25 or ≥25 kg/m2), Nicotine Use (Yes/No), Gestational length (continuous variable, weeks), Chronic diseases (Yes/No)
  2. aExclude all non-emergency Caesarean Section (CS)
  3. bNon adjusted for gestational length but for all other covariates
  4. cAdjusted for usual covariates, CS and Hypertensive disorders
  5. dAdjusted for usual covariates and CS
  6. eExclude all CS
  7. fHypertensive disorders including preeclampsia, pregnancy induced hypertension,eclampsia or HELLP
  8. *p < 0.05
  9. **p < 0.01
  10. ***p < 0.001
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