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Table 1 General characteristics of the women population with spontaneous abortion (SA) and non-SA at the time of enrollment in the Health Examinee Study (HEXA), a cohort study of the Korean Genome and Epidemiology Study (KoGES) in the Korea Center for Disease Control and Prevention (KCDC), 2004-2012

From: Body mass index at age 18–20 and later risk of spontaneous abortion in the Health Examinees Study (HEXA)

No.=80,447

Spontaneous Abortion

 

No

Yes

N=62,637

N=17,810

 

N (%)

N (%)

p-value*

Attained education ≥12 years

14,598 (23.3)

4,484 (25.2)

<0.001

Cigarette smoking before the first pregnancy

538 (0.859)

154 (0.865)

0.002

Ever consumed alcohol1

21,222 (33.9)

6,139 (34.5)

<0.001

Regular exercise

32,437 (51.8)

9,211 (51.7)

0.305

Medical history before pregnancy

  

 Hypertension

37 (0.06)

9 (0.05)

0.687

 Diabetes

20 (0.02)

3 (0.02)

0.291

 Chronic liver disease

154 (0.25)

35 (0.20)

0.266

 Tuberculosis

2,067 (3.30)

587 (3.30)

0.878

 Thyroid disease

211 (0.34)

73 (0.41)

0.138

Reproductive factors

   

 Menarche age (years)

  

0.071

  ≤14

23,559 (37.6)

6,830 (38.4)

 

  15

14,077 (22.5)

3,845 (21.6)

 

  ≥16

23,903 (38.2)

6 816 (38.3)

 

 First pregnancy age

  

<0.001

  ≤23

19,199 (30.7)

5,093 (28.6)

 

  24–26

25,066 (40.0)

7,029 (39.5)

 

  ≥27

18,372 (29.3)

5,688 (31.9)

 

 First pregnancy outcome

   

 Stillbirth

393 (0.63)

178 (1.00)

<0.001

 Extrauterine pregnancy

195 (0.31)

67 (0.38)

0.184

 Artificial abortion

7,467 (12.0)

1,466 (8.3)

 

 Number of children

  

<0.001

  1

6,358 (10.2)

2,062 (11.8)

 

  2

37,754 (60.8)

9,974 (57.0)

 

  3+

17,866 (28.8)

5,420 (30.1)

 

 Gestational diabetes

569 (0.91)

211 (1.18)

<0.001

 Gestational hypertension

2,966 (4.7)

1,065 (6.0)

<0.001

 Macrosomia (>4.0kg)

4,406 (7.0)

1,646 (8.2)

<0.001

 Microsomia (<2.5kg)

2,390 (3.8)

995 (5.6)

<0.001

  1. *p–value from χ2–test
  2. 1Due to lack of information about age of beginning of drinking, usual drinkers were included in this category