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Table 3 Associations between mothers' alcohol consumption and foetal health outcomes in Northern Tanzania 2000–2010

From: Alcohol consumption among pregnant women in Northern Tanzania 2000–2010: a registry-based study

 

% of births

% (n) of births with outcome

Univariate analysis

Multivariable model(a)

Variables

RR (95 % CI)

p-value

ARR (95 % CI)

p-value

Perinatal death (n = 33971)(b)

 Drinks alcohol

34.1

5.2 (606)

0.83 (0.76 – 0.91)

< 0.001

0.93 (0.81 – 1.07)

0.288

 Drinks alcohol every day

1.0

3.3 (11)

0.53 (0.30 – 0.95)

0.032

0.40 (0.17 – 0.96)

0.041

 Drinks alcohol more than once a week

10.1

4.6 (157)

0.72 (0.62 – 0.85)

<0.001

0.81 (0.64 – 1.01)

0.064

 Drinks alcohol once a week

3.8

5.1 (66)

0.80 (0.63 – 1.02)

0.073

1.05 (0.77 – 1.44)

0.743

 Drinks occasionally

19.2

5.7 (372)

0.90 (0.81 – 1.01)

0.071

0.99 (0.85 – 1.16)

0.930

 Abstains from alcohol

65.9

6.3 (1414)

1.00

 

1.00

 

Small for gestational age (below 10th percentile related to gestational age and sex(d)) (n = 27065)(c)

 Drinks alcohol

34.4

14.0 (1305)

0.81 (0.76 – 0.86)

< 0.001

0.87 (0.80 – 0.94)

0.001

 Drinks alcohol every day

1.0

13.8 (36)

0.80 (0.59 – 1.08)

0.142

0.81 (0.54 – 1.22)

0.316

 Drinks alcohol more than once a week

10.0

13.5 (367)

0.78 (0.71 – 0.86)

< 0.001

0.88 (0.77 – 1.00)

0.052

 Drinks alcohol once a week

4.0

14.2 (153)

0.82 (0.70 – 0.95)

0.009

0.80 (0.65 – 0.98)

0.034

 Drinks occasionally

19.4

14.3 (749)

0.82 (0.77 – 0.89)

< 0.001

0.88 (0.79 – 0.97)

0.007

 Abstains from alcohol

65.6

17.3 (3079)

1.00

 

1.00

 

Low gestational age < 37 weeks (n = 29399)(c)

 Drinks alcohol

34.4

10.5 (1062)

0.85 (0.79 – 0.91)

< 0.001

0.89 (0.81 – 0.99)

0.024

 Drinks alcohol every day

1.0

11.7 (33)

0.95 (0.69 – 1.31)

0.735

0.93 (0.61 – 1.41)

0.723

 Drinks alcohol more than once a week

10.1

10.1 (301)

0.82 (0.73 – 0.92)

< 0.001

0.90 (0.77 – 1.05)

0.170

 Drinks alcohol once a week

4.0

10.5 (123)

0.85 (0.71 – 1.00)

0.055

0.91 (0.72 – 1.15)

0.450

 Drinks occasionally

19.4

10.6 (605)

0.86 (0.79 – 0.93)

< 0.001

0.88 (0.78 – 1.00)

0.043

 Abstains from alcohol

65.6

12.4 (2394)

1.00

 

1.00

 

Low Apgar score 5 min after birth (Apgar score < 7) (n = 32363)(b)

 Drinks alcohol

34.2

2.7 (304)

0.87 (0.76 – 0.99)

0.039

1.12 (0.92 – 1.36)

0.249

 Drinks alcohol every day

1.0

2.2 (7)

0.70 (0.34 – 1.47)

0.348

0.48 (0.12 – 1.94)

0.300

 Drinks alcohol more than once a week

10.2

2.6 (85)

0.82 (0.65 – 1.02)

0.076

1.28 (0.95 – 1.73)

0.104

 Drinks alcohol once a week

3.8

2.3 (29)

0.74 (0.51 – 1.06)

0.103

1.23 (0.78 – 1.95)

0.371

 Drinks occasionally

19.2

2.9 (183)

0.93 (0.79 – 1.09)

0.384

1.10 (0.88 – 1.38)

0.386

 Abstains from alcohol

65.8

3.2 (673)

1.00

 

1.00

 
  1. (a)In the multivariable analyses the associations with alcohol have for all the outcomes been adjusted for the following predictors: mother's age, mother's occupation, mother's tribe, mother's religion, mother's body mass index, mother's height, previous pregnancies, mother's current residence, mother's childhood residence, father's age, father's tribe, year of delivery, drinking water source, boiling of drinking water, mother's age at marriage and mother's HIV-status
  2. (b)Analyses of perinatal death and low Apgar score 5 min after birth includes all births including twins and triplets. Low Apgar score does not include stillbirths
  3. (c)Analyses of small for gestational age and low gestational age include singleton births only
  4. (d)Limits for 10th percentile related to gestational age and sex are based on Villar et al., 2014