From: Maternal psychiatric disease and epigenetic evidence suggest a common biology for poor fetal growth
Gene and locus | Methylation (adjusted Beta) | No psychiatric diagnosis and no antidepressant (n = 159) | Psychiatric diagnosis and no antidepressant (n = 13) | Psychiatric diagnosis and antidepressant (n = 12) | FDR adjusted p-value (Fisher’s exact test) |
---|---|---|---|---|---|
 |  | 59/159 (37.1 %) | 10/13 (76.9 %) | 9/12 (75.0 %) |  |
had SGA or IUGR | had SGA or IUGR | had SGA or IUGR | |||
FKBP5 | <= Median | 79 (49.7 %) | 4 (30.8 %) | 8 (66.7 %) | 3.7 × 10−01 |
cg08636224 | > Median | 80 (50.3Â %) | 9 (69.2Â %) | 4 (33.3Â %) | |
RPE65 | <= Median | 85 (53.5 %) | 4 (30.8 %) | 6 (50.0 %) | 3.7 × 10−01 |
cg11724759 | > Median | 74 (46.5Â %) | 9 (69.2Â %) | 6 (50.0Â %) | |
LEPRa | <= Median | 76 (47.8 %) | 12 (92.3 %) | 5 (41.7 %) | 2.9 × 10−02 |
cg21655790 | > Median | 83 (52.2Â %) | 1 (7.7Â %) | 7 (58.3Â %) | |
LEPROTL1 | <= Median | 80 (50.3 %) | 6 (46.2 %) | 3 (25.0 %) | 3.7 × 10−01 |
cg00177923 | > Median | 79 (49.7Â %) | 7 (53.9Â %) | 9 (75.0Â %) | |
NFKBIZ | <= Median | 76 (47.8 %) | 11 (84.6 %) | 6 (50.0 %) | 1.1 × 10−01 |
cg26284390 | > Median | 83 (52.2Â %) | 2 (15.4Â %) | 6 (50.0Â %) | |
NFKBIZ | <= Median | 80 (50.3 %) | 8 (61.5 %) | 5 (41.7 %) | 6.5 × 10−01 |
cg15006396 | > Median | 79 (49.7Â %) | 5 (38.5Â %) | 7 (58.3Â %) |