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Table 2 Baseline and Postpartum levels of Angiogenic and oxidative biomarkers among the studied groups

From: Association between adverse pregnancy outcome and imbalance in angiogenic regulators and oxidative stress biomarkers in gestational hypertension and preeclampsia

Parameters

NP

GH

PE

Pre-delivery

48 h postpartum

Pre-delivery

48 h postpartum

Pre-delivery

48 h postpartum

Angiogenic Factors

      

 PLGF (pg/ml)

137.7

187.9**

53.05

163.9***

21.40

96.3***

(88.1–177.8)

(130.7–214.6)

(38.33–74.80)

(94.00–200.3)

(12.40–48.40)

(77.3–131.0)

 sFlt-1 (pg/ml)

119.5

45.6***

413.2

77.3***

787.6

104.6***

(87.4–160.4)

(19.28–88.7)

(164.5–635.0)

(44.4–101.6)

(510.7–926.3)

(66.3–139.0)

 sFlt-1/PLGF

0.9

0.2***

7.8

0.5***

36.80

1.1***

(0.6–1.2)

(0.2–0.5)

(5.4–12.8)

(0.2–0.7)

(16.42–56.92)

(0.3–2.0)

 PLGF/sFlt-1

1.1

3.4**

0.1

2.2***

0.0351

0.9***

(0.5–2.0)

(1.9–9.5)

(0.1–0.5)

(1.0–3.7)

(0.015–0.085)

(0.5–1.7)

Oxidative biomarkers

      

 8-epi-PGF2α (pg/ml)

35.7

15.8**

198.8

18.4***

324.6

66.3***

(28.7–42.9)

(12.2–18.7)

(92.48–392.3)

(12.0–32.1)

(194.2–618.6)

(32.65–100.4)

 TAOC (mmol/l)

1.1

1.2*

0.6

0.8*

0.5

0.7***

(1.0–1.2)

(1.1–1.3)

(0.4–0.8)

(0.6–1.1)

(0.2–0.6)

(0.4–0.9)

  1. Values are presented as median (Interquartile range). *p < 0.05; **p < 0.001; ***p < 0.0001