Maternal creatine homeostasis is altered during gestation in the spiny mouse: is this a metabolic adaptation to pregnancy?

Table 5 Tissue Creatine Content

Tissue creatine content	Non-pregnant	Pregnant	Statistics
	*Estimated Total Creatine per Organ (nmol)*
Kidney	520.9 ± 48.36	912.61 ± 48.36	<0.001
Liver	2432.4 ± 548.3	2554.1 ± 557.8	NS
Brain	14443.0 ± 399.9	12933.7 ± 1109.5	NS
Heart	1540.4 ± 107.7	1899.9 ± 72.36	<0.05
	*Total Creatine (mmol/kg Dry Weight)*
Gastrocnemius Muscle	136.1 ± 9.4	124.1 ± 3.0	NS

Estimated total creatine content per organ (nmol). Data calculated from total creatine content, wet/dry weight ratio and wet mass per organ, except for the gastrocnemius muscle (mmol/kg dry mass). Values are means ± SEM; n = 6/group. Statistical analysis Students t-Test. Significance P ≤ 0.05.

ISSN: 1471-2393