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Table 1 Baseline characteristics at early pregnancy stratified by tertiles of Hb changes from early to late pregnancy (n = 1986) a, b

From: Changes in maternal hemoglobin during pregnancy and birth outcomes

Characteristics

Total (n = 1986)

Greatest reduction (Hb change < −1.9) (n = 639)

Intermediate reduction (−1.9 ≤ Hb change < −1.0) (n = 689)

Least reduction (Hb change ≥ −1.0) (n = 658)

Maternal age, (years)

35.5 (4.2)

35.6 (4.1)

35.4 (4.2)

35.4 (4.4)

Pre-pregnancy BMI, (kg/m2)

20.3 (2.6)

20.5 (2.7)

20.3 (2.5)

20.0 (2.6)

Maternal weight gain until delivery, (kg)

9.6 (3.4)

9.5 (3.4)

9.7 (3.5)

9.6 (3.2)

Parity

    

  0, n (%)

1057 (53.2)

296 (46.3)

373 (54.1)

388 (59.0)

  1, n (%)

730 (36.8)

273 (42.7)

251 (36.4)

206 (31.3)

  ≥2, n (%)

199 (10.0)

70 (11.0)

65 (9.4)

64 (9.7)

ART, n (%)

310 (15.6)

101 (15.8)

108 (15.7)

101 (15.3)

Maternal pre-pregnancy complications

   

  Hypertension, n (%)

25 (1.3)

11 (1.7)

9 (1.3)

5 (0.76)

  Autoimmune disease, n (%)

44 (2.2)

14 (2.2)

15 (2.2)

15 (2.3)

  Basedow’s disease, n (%)

28 (1.4)

10 (1.6)

13 (1.9)

5 (0.76)

  Hypothyroid, n (%)

51 (2.6)

13 (2.0)

22 (3.2)

16 (2.4)

Smoking

    

  Never or former, n (%)

1981 (99.7)

638 (99.8)

688 (99.9)

655 (99.5)

  Current, n (%)

5 (0.25)

1 (0.16)

1 (0.15)

3 (0.46)

Alcohol intake

    

  Current, n (%)

158 (8.0)

48 (7.5)

58 (8.4)

52 (7.9)

MAP at early pregnancy, (mmHg)c

79.5 (9.6)

80.8 (9.7)

79.5 (9.6)

78.2 (9.4)

  1. aValues are presented as mean (SD) for continuous variables and n (%) for dichotomous variables.
  2. bHb tertiles were calculated from the distribution of Hb changes from early to late pregnancy (i.e., Hb at late pregnancy - Hb at early pregnancy).
  3. cCalculated as (2 x diastolic BP + systolic BP)/3.
  4. ART, artificial reproductive technology; MAP, mean arterial pressure; SD, standard deviation.