From: Uterine artery Doppler in the management of early pregnancy loss: a prospective, longitudinal study
All n(%) 315(100) | p-value1 | Group I n(%) 142(45) | p-value1 | Group II n(%) 141(45) | p-value1 | Group III n(%) 32(10) | p-value1 | ||
---|---|---|---|---|---|---|---|---|---|
Age (in years) | 20-24 | 36(12) | <0.001 | 18(13) | <0.001 | 14(10) | <0.001 | 4(12) | 0.030 |
25-34 | 159(50) | 67(47) | 76(54) | 16(50) | |||||
35-46 | 120(38) | 57(40) | 51(36) | 12(38) | |||||
Education level (in years) | ≤9 | 115(37) | <0.001 | 55(39) | <0.001 | 48(34) | <0.001 | 12(38) | 0.197 |
10-12 | 146(46) | 60(42) | 72(51) | 14(44) | |||||
>12 | 54(17) | 27(19) | 21(15) | 6(19) | |||||
Parity | 0 | 171(54) | 0.128 | 64(45) | 0.240 | 49(49) | 0.842 | 25(78) | 0.001 |
≥1 | 144(46) | 78(55) | 51(51) | 7(22) | |||||
Previous spontaneous first trimester miscarriage (≤12 weeks) | 1 | 277(88) | <0.001 | 125(88) | <0.001 | 124(88) | <0.001 | 28(88) | <0.001 |
>1 | 38(12) | 17(12) | 17(12) | 4(12) | |||||
Body Mass Index (Kg/m2) | 16-24 | 142(45) | <0.001 | 72(51) | <0.001 | 53(38) | 0.001 | 17(53) | 0.001 |
25-29 | 134(43) | 58(41) | 62(44) | 14(44) | |||||
30-44 | 39(12) | 12(8) | 26(18) | 1(3) | |||||
Smoking | No | 243(77) | <0.001 | 103(39) | <0.001 | 115(82) | <0.001 | 25(78) | 0.001 |
Yes | 72(23) | 73(27) | 26(18) | 7(22) | |||||
GA at early pregnancy loss diagnosis [weeks (SD)] | 8.0(1.3) | 7.6(1.0) | 8.2(1.3) | 9.1(1.3) | |||||
Uterine arteries Doppler assessment [days (SD)] | 18.2(2.8) | 18.0(2.4) | 18.3(3.2) | 18.9(2.6) | |||||
Intra-uterine content thickness [mm (SD)] | 11.8(5.8) | 6.1(2.5) | 15.8(2.3) | 19.6(2.3) | |||||
Uterine content thickness at 2nd week follow-up visit | <12 mm | 148(0.53) | 0.328 | 142(100) | 0 | 0 | |||
≥12 mm | 167(0.47) | 0 | 141(100) | 32(100) | |||||
Uterine artery Doppler - Bilateral notching | No | 3(1) | <0.001 | 0 | <0.001 | 1(1) | <0.001 | 2(6) | <0.001 |
Yes | 312(99) | 142(100) | 140(99) | 30(94) | |||||
Decision for D&C at 8th week follow-up visit | No | 283(90) | <0.001 | 142(100) | 141(100) | 0 | |||
Yes | 32(10) | 0 | 0 | 32(100) |