Table 3 Rate (%) and adjusted odds ratios (aORs) of adverse neonatal outcomes associated with BMI, GWG and prenatal smoking*

All women (n = 71,200)

6.1

8.1

11.3

Prepregnancy BMI

<18.5

8.4

1.55 [0.96 , 2.52]

20.5

2.04 [1.46, 2.84]

4.3

0.64 [0.33, 1.20]

18.5-24.9

5.6

Reference

10.0

Reference

7.5

Reference

25.0-29.9

6.1

0.98 [0.72, 1.33]

8.2

0.95 [0.74, 1.22]

11.4

1.38 [1.08, 1.75]

≥30

7.4

1.02 [0.73,1.42]

8.6

0.86 [0.63, 1.15]

14.1

1.89 [1.45, 2.47]

Gestational weight gain

< recommended

6.5

1.35 [0.92, 1.97]

16.1

1.56 [1.20, 2.03]

4.6

0.57 [0.39, 0.84]

= recommended

4.5

Reference

10.9

Reference

7.7

Reference

> recommended

6.7

1.45 [1.06, 1.98]

7.7

0.70 [0.56, 0.87]

11.0

1.34 [1.04, 1.72]

Smoked 3^rd trimester

Yes

8.9

1.31 [0.92, 1.86]

18.4

2.06 [1.59, 2.67]

2.8

0.26 [0.16, 0.43]

No

5.8

Reference

9.1

Reference

9.7

Reference

Primigravidas (n = 24,000)

6.8

10.5

7.5

Prepregnancy BMI

<18.5

8.7

1.63 [0.77, 3.47]

28.3

2.47 [1.53, 3.99]

0.8

0.14 [0.005, 4.69]

81.5-24.9

6.1

Reference

12.2

Reference

6.1

Reference

25.0-29.9

8.6

1.30 [0.80, 2.12]

10.4

0.89 [0.59, 1.34]

7.5

1.12 [0.67, 1.87]

≥30

6.6

0.86 [0.45, 1.66]

12.1

0.97 [0.61, 1.57]

11.4

1.89 [1.11, 3.21]

Gestational weight gain

< recommended

6.6

1.60 [0.78, 3.29]

20.8

1.40 [0.92, 2.12]

2.1

0.49 [0.17, 1.41]

= recommended

3.9

Reference

15.9

Reference

4.1

Reference

> recommended

7.9

2.02 [1.13, 3.63]

9.9

0.61 [0.44, 0.86]

8.8

2.01 [1.12, 3.61]

Smoked 3^rd trimester

Yes

8.2

1.04 [0.53, 2.04]

27.4

2.32 [1.49, 3.62]

2.1

0.29 [0.08, 1.13]

No

6.7

Reference

11.8

Reference

7.0

Reference

Multigravidas, previous PTB (n = 4,000)

13.3

7.4

10.9

Prepregnancy BMI

<18.5

8.6

0.70 [0.05, 9.26]

19.7

1.79 [0.20, 15.69]

0

--^b

18.5-24.9

15.0

Reference

9.3

Reference

7.2

Reference

25.0-29.9

9.5

0.56 [0.19, 1.67]

6.8

1.14 [0.26, 4.92]

10.6

1.58 [0.33, 7.49]

≥30

14.9

0.89 [0.36, 2.22]

5.9

0.42 [0.08, 2.18]

3.8

0.55 [0.07, 4.34]

Gestational weight gain

< recommended

13.1

0.83 [0.22, 3.10]

17.1

1.40 [0.35, 5.58]

6.9

1.24 [0.08, 18.45]

= recommended

15.6

Reference

12.8

Reference

4.6

Reference

> recommended

12.5

0.93 [0.33, 2.59]

4.5

0.30 [0.08, 1.14]

7.7

1.01 [0.14, 7.45]

Smoked 3^rd trimester

Yes

16.0

1.45 [0.46, 4.61]

12.8

1.77 [0.43, 7.24]

0

--^b

No

12.8

Reference

7.8

Reference

8.3

Reference

Multigravidas, no previous PTB, previous loss^a (n = 21,300)

6.2

7.1

11.8

Prepregnancy BMI

<18.5

10.3

1.90 [0.73, 4.93]

14.2

1.75 [0.84, 3.66]

6.7

1.04 [0.37, 2.90]

18.5-24.9

5.7

Reference

9.2

Reference

7.5

Reference

25.0-29.9

5.9

1.00 [0.57, 1.75]

6.4

0.72 [0.44, 1.19]

12.3

1.53 [1.00, 2.36]

≥30

7.2

0.92 [0.47, 1.80]

8.3

0.84 [0.46, 1.54]

16.9

2.61 [1.61, 4.23]

Gestational weight gain

< recommended

8.1

1.14 [0.59, 2.19]

14.2

1.65 [0.96, 2.83]

5.0

0.41 [0.20, 0.81]

= recommended

5.9

Reference

8.2

Reference

9.9

Reference

> recommended

5.7

0.93 [0.53, 1.62]

7.1

0.83 [0.50, 1.36]

11.4

1.02 [0.64, 1.63]

Smoked 3^rd trimester

Yes

8.8

1.77 [0.97, 3.23]

16.3

2.26 [1.40, 3.64]

10.8

0.23 [0.10, 0.51]

No

5.8

Reference

7.5

Reference

3.6

Reference

Multigravidas, no previous PTB, no previous loss^a (n = 21,600)

4.0

6.7

14.9

Prepregnancy BMI

<18.5

6.1

2.14 [0.56, 8.20]

15.3

1.81 [0.84, 3.88]

6.9

0.93 [0.31, 2.76]

18.5-24.9

3.5

Reference

8.1

Reference

9.3

Reference

25.0-29.9

3.3

0.75 [0.37, 1.51]

8.3

1.24 [0.76, 2.03]

14.2

1.46 [0.99, 2.14]

≥30

6.5

1.21 [0.59, 2.50]

6.2

0.78 [0.38, 1.61]

16.8

1.79 [1.14, 2.80]

Gestational weight gain

< recommended

3.8

1.98 [0.71, 5.51]

13.6

1.76 [1.03, 3.03]

6.2

0.66 [0.34, 1.26]

= recommended

2.1

Reference

8.2

Reference

9.9

Reference

> recommended

4.9

2.52 [0.99, 6.37]

6.4

0.80 [0.49, 1.30]

13.8

1.36 [0.88, 2.08]

Smoked 3^rd trimester

Yes

7.0

1.13 [0.50, 2.59]

15.2

1.92 [1.10, 3.35]

3.3

0.29 [0.12, 0.71]

No

3.7

Reference

7.6

Reference

12.1

Reference