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Table 3 Reported adverse events in all included trials

From: Atosiban versus betamimetics in the treatment of preterm labour in Germany: an economic evaluation

Adverse event Frequency (%)
Atosiban
Frequency (%)
Betamimetics
Relative risk and Confidence Intervals p-value
Tachycardia 3.90% 56.30% RR = 0.07,
95% CI = 0.05, 0.1
<0.001
Palpitation 2.40% 20.40% RR = 0.12,
95% CI = 0.06, 0.22
<0.001
Vomiting 5.90% 19.20% RR = 0.27,
95% CI = 0.18, 0.4
<0.001
Headache 8.40% 14.10% RR = 0.59,
95% CI = 0.43, 0.8
<0.001
Hyperglycaemia 7.80% 13.30% RR = 0.57,
95% CI = 0.4, 0.89
0.001
Tremor 0.80% 12.20% RR = 0.08,
95% CI = 0.04, 0.19
<0.001
Nausea 8.70% 10.50% RR = 0.79,
95% CI = 0.57, 1.08
0.135
Dyspnoea 0.60% 8.50% RR = 0.09,
95% CI = 0.04, 0.23
<0.001
Chest pain 1.70% 8.00% RR = 0.18,
95% CI = 0.09, 0.38
<0.001
Hypokalemia 0.70% 7.10% RR = 0.13,
95% CI = 0.05, 0.36
<0.001
Hypotension 2.80% 5.00% RR = 0.6,
95% CI = 0.29, 1.11
0.1
Anxiety 1.50% 3.80% RR = 0.43,
95% CI = 0.2, 0.91
0.027
Syncope 0.60% 0.50% RR = 1.02,
95% CI = 0.17, 5.98
0.984
Pulmonary oedema 0.30% 0.50% RR = 0.6,
95% CI = 0.08, 4.45
0.614
Myocardial ischemia 0.00% 0.30% RR = 0.34,
95% CI = 0.01, 8.3
0.509
Foetal tachycardia 2.90% 21.10% RR = 0.14,
95% CI = 0.08, 0.23
<0.001