Women's attitude towards prenatal screening for red blood cell antibodies, other than RhD

Table 6 Opinion about burden and usefulness of RBC antibodies and HDFN 2 weeks after birth, according to HDFN risk, as established upon first trimester RBC antibody screening

	Controls	Screen-positive, not at risk HDFN			At risk HDFN
	n = 73¹	Screen-pos, not-confirmed n = 21	Clinically non-relevant antibodies n = 44	Non-RhD antibodies, father neg. n = 30	Non-RhD-antibodies, father positive n = 45
	%	%	%	%	%
*Perceived burden of the screening process 20th week of pregnancy*
.no burden ²	99	52*	45*	60*	29*
.some burden	1	48	55	30	62
.significant burden	0	0	0	10	9
*Perceived burden of the screening process 2 weeks after birth*
.no burden ²	99	67*	51*	67*	47*
.some burden	1	33	49	27	47
.significant burden	0	0	0	6	6
*Opinion on usefulness of the screening 2 weeks after birth*
.not useful ²	8	19	22**	13	4
.some usefulness	60	43	45	57	56
.significant usefulness	32	38	33	30	40
*Opinion on balance usefulness versus burden of screening 2 weeks after birth*
for myself
. unimportant ²	7	0	9	4	4
. some importance	42	62	47	46	29
. important	51	38	44	50	67
for others
. unimportant	5	5	12	4	4
. some importance	46	52	38	46	35
. important	49	43	50	50	61

¹ Weighted controls from hospital care: 35*0.41 = 15; 58 controls from midwifery care
² No burden/not useful/unimportant: VAS score < 3.4; some burden/usefulness/importance: VAS score between 3.4 and 6.9; significant burden/usefulness/important: VAS score >= 6.9 (see methods).
* p < 0.05, difference compared to controls **significant more 'no' than in control group (p 0.034)

ISSN: 1471-2393