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Table 2 Outcomes after receiving study treatment

From: Misoprostol in addition to routine treatment of postpartum hemorrhage: A hospital-based randomized-controlled trial in Karachi, Pakistan

 

misoprostol

placebo

 
 

n = 29

n = 32

RR [95% CI] or p-value

Postpartum blood loss after study treatment

   
 

(n = 27) ^

(n = 32)

 

Total blood loss post-treatment (ml)

   

   mean ± sd

175 ± 168

187 ± 207

p = .809

   Range

10–700

10–900

 

Blood loss ≥ 500 ml post-treatment %(n)

7.4 (2)

12.5 (4)

.59 [.12, 2.99]

Postpartum hemoglobin measures

   

Post-delivery Hb

   

   mean ± sd

9.0 ± 1.4

8.7 ± 1.2

p = .291

   range

5.9 – 11.3

5.9 – 10.2

 

Drop in Hb

   

   mean ± sd

2.0 ± 1.1

2.2 ± 1.4

p = .614

   range

0.4 – 4.2

0.1 – 5.1

 

Postpartum Hb ≥ 2 g/dL lower than pre-delivery Hb %(n)

41.4 (12)

56.3 (18)

.74 [.43, 1.25]

Additional interventions

   

Amount of IV fluids given

   

   500–1000 ml

75.9 (22)

53.1 (17)

 

   > 1000 ml

24.1 (7)

46.9 (15)

.51 [.24, 1.08]

Blood transfusion %(n)

17.2 (5)

18.8 (6)

.92 [.31, 2.69]

Uterine packing %(n)

6.9 (2)

18.8 (6)

.37 [.08, 1.68]

Balloon tamponade %(n)

0.0 (0)

3.1 (1)

.00 [.00, 43.0]

Referrals for additional PPH care %(n)

3.4 (1)

3.2 (1)

1.1 [.07, 16.9]

  1. ^ Two cases in the misoprostol arm have incomplete blood loss measurements and were excluded from analysis of measured postpartum blood loss.