Small for gestational age | ||||
---|---|---|---|---|
Analyte Subgroup | Positive Likelihood Ratio (95% CI) | Negative Likelihood Ratio (95% CI) | Sensitivity (95% CI) | Specificity (95% CI) |
HCG>90 th centile (BW<10th centile) | ||||
Trimester | Â | Â | Â | Â |
First | 1.48 (0.57–3.81) | 0.92 (0.72–1.17) | 0.21 (0.06–0.46) | 0.86 (0.79–0.91) |
Second | 1.68 (0.37–7.63) | 0.97 (0.86–1.09) | 0.08 (0.01–0.26) | 0.95 (0.90–0.98) |
HCG<10 th centile (BW<10th centile) | ||||
Trimester | Â | Â | Â | Â |
First | 1.29 (0.05–33.56) | 1.14 (0.53–2.43) | 0.13 (0.10–0.16) | 0.60 (0.57–0.63) |
Second | 2.35 (0.80–6.92) | 0.90 (0.76–1.08) | 0.16 (0.05–0.36) | 0.93 (0.88–0.97) |
HCG>2.0MoM (BW<5th centile) | ||||
Trimester | Â | Â | Â | Â |
First | 0.96 (0.55–1.68) | 1.01 (0.88–1.17) | 0.20 (0.10–0.34) | 0.79 (0.77–0.81) |
Second | 2.08 (1.78–2.42) | 0.94 (0.92–0.95) | 0.12 (0.10–0.14) | 0.94 (0.94–0.95) |
PAPPA<10 th centile (BW<10 th centile) | ||||
Trimester | Â | Â | Â | Â |
First | 1.68 (1.25–2.27) | 0.93 (0.88–0.98) | 0.17 (0.16–0.19) | 0.90 (0.89–0.90) |
Second | 1.82 (0.95–3.50) | 0.91 (0.75–1.05) | 0.20 (0.10–0.33) | 0.89 (0.85–0.92) |
Pre-eclampsia | ||||
HCG>2.0MoM | ||||
Trimester | Â | Â | Â | Â |
First | 1.77 (1.07–2.92) | 0.80 (0.60–1.07) | 0.37 (0.19–0.58) | 0.79 (0.77–0.81) |
Second | 2.45 (1.57–3.84) | 0.89 (0.83–0.96) | 0.19 (0.17–0.21) | 0.93 (0.93–0.93) |