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Table 1 For each sub-group (PROM or SPL), a response from 3700 babies will allow the following differences to be detected with 80% power:

From: MRC ORACLE Children Study. Long term outcomes following prescription of antibiotics to pregnant women with either spontaneous preterm labour or preterm rupture of the membranes

Outcome Incidence in erythromycin group Incidence in erythromycin placebo group Relative risk reduction
'3 or more attributes affected' 3.1% 5% 38%
  5.6% 8% 30%
  1.5% 3% 50%