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Table 3 The MAPK signaling pathway differentially expressed in the myometrium

From: Functional genomics of the pregnant uterus: from expectations to reality, a compilation of studies in the myometrium

MAPK signaling pathway

NP-TNIL1 (15)

PTNIL-TNIL2 (12)

TNIL-TIL3 (4)

CD14(+)

EGF(+)

BDNF(+)

EGFR(+)

IKBKB(+)

DUSP5(+)

FGFR1(+)

MAP2K4(+)

NR4A1(+)

FLNA(+)

MAPK10(+)

TGFB2(+)

HSPA5(+)

PLA2G5(+)

 

HSPA8(+)

RAP1A(+)

 

MAP3K5(+)

RASA1(+)

 

NLK(+)

TNF(+)

 

PLA2G2A(+)

TP53(+)

 

PRKCB1(+)

PLA2G2A(-)

 

PRKCG(+)

PPP5C(-)

 

RAC2(+)

TNFRSF6(-)

 

RASGRP2(+)

  

RRAS(+)

  

YWHAZ(+)

  
  1. Genes detected in genomic studies according to 1NP-TNIL, to 2PTNIL-TNIL or to 3TNIL-TIL comparisons, during the cycle or pregnancy. Brackets: number of genes represented in the pathway. All gene transcripts showed at least a 2-fold or more, up (+) or down-regulation (-) after paired comparisons of the following stages: non-pregnant (NP) versus term not in labor (TNIL), preterm (PTNIL) versus TNIL, or TNIL versus term in labor (TIL). OMIM nomenclature [34] adopted for gene names.