Figure 1From: Tocolytic effect of a selective FP receptor antagonist in rodent models reveals an innovative approach to the treatment of preterm laborEffects of AS604872 and ritodrine on inhibition of spontaneous uterine contractions in pregnant rats. Anesthetized late-term pregnant rats at gestational days 19–21 were treated with AS604872 or ritodrine either by intravenous route as a 10-min infusion or orally as a single dose. The inhibition of spontaneous uterine contractions is represented in function of the dose of drugs. N = 8 animals per dose and route and drug. *p < 0.05, **p < 0.01 and ***p < 0.001 vs vehicle-treated group (one-way ANOVA followed by Tukey test).Back to article page