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Table 4 Single versus double layer closure of the uterus

From: The CORONIS Trial. International study of caesarean section surgical techniques: a randomised fractional, factorial trial

Study

n

Infection

Blood loss

Health service use

Other outcomes

  

Outcome

Result

Outcome

Result

Outcome

Result

Outcome

Result

Cochrane review 15

1,006

Endometritis (n = 784) (RR)

1.22 (0.91–1.63)

Transfusion (n = 906) (RR)

0.80 (0.34–1.92)

Operating time (Mean)

43.8 v 47.5 min

Moderate or major deformity of

0.19 (0.06–0.60)

    

Extra haemostatic sutures (n = 906) (RR)

0.93 (0.79–1.08)

  

scar on radiography (n = 100) (RR)

 
    

>8% drop in haematocrit (n = 906) (RR)

1.09 (0.86–1.38)

    

Heidenreich 17

125

Post-operative fever

4.8% v. 7.2%

Transfusion

3.8% v. 3.2%

  

Scar thickness by US (8–10 days after surgery)

0.72 v. 0.82 cm

Sood 18

208

Febrile morbidity (RR)

0.50 (0.27–0.94)

Intraoperative blood loss (Mean)

600 v. 629.6 ml

Operating time (Mean)

Hospital stay (Mean)

31.3 v. 33.1 min

6.67 v. 7.19 days

Pain (VAS Score) (Mean)

2.91 v. 3.05

  

Endometritis (RR)

0.44 (0.20–0.95)

Additional suture (RR)

1.36 (0.85–2.17)

    
  

Wound infection (RR)

0.46 (0.15–1.45)