Table 2 Risk of open neural tube defects in relation to certain maternal features of the metabolic syndrome (MetSyn)
From: Metabolic Syndrome features and risk of neural tube defects
Prevalence of MetSyn | Odds ratio (95% CI) | |||||
|---|---|---|---|---|---|---|
Model | No. features of MetSyn | No. (%) cases | No. (%) controls | Crude | Adjusted** | P-value for trend |
Without hsCRP as a feature of MetSyn | 0 (n = 382) | 54 (60.7) | 328 (75.6) | 1.0 (ref) | 1.0 (ref) | 0.001 |
1 (n = 135) | 32 (36.0) | 103 (23.7) | 1.9 (1.2–3.1) | 1.9 (1.1–3.4) | ||
≥ 2 (n = 6) | 3 (3.4) | 3 (0.69) | 6.1 (1.2–30.9) | 6.1 (1.1–32.9) | ||
With hsCRP as a feature of MetSyn* | 0 (n = 351) | 50 (56.2) | 301 (69.4) | 1.0 (ref) | 1.0 (ref) | 0.009 |
1 (n = 147) | 32 (36.0) | 115 (26.5) | 1.7 (1.0–2.7) | 1.6 (0.88–2.8) | ||
≥ 2 (n = 25) | 7 (7.8) | 18 (4.1) | 2.3 (0.93–5.9) | 3.1 (1.2–8.3) | ||