Table 2 Summary of cases with elevated MSAFP levels

Patent ductus arteriosus, patent foramen ovale, dysmorphic skull, low set left ear

Cystic hygroma, left pleural effusion, cardiac anomalies (unspecified), abnormal limb position, oligohydramnios

Epicanthic folds, hypertelorism, short nose with a long philtrum, hypoplastic toenails

Cerebral dysgenesis, ascites, cardiac hypertrophy, amputation of both hands and feet, ambiguous external genitalia

Esophageal atresia, tracheo-esophageal fistula, hemivertebrae, absent septum pellucidum, choroid plexus cyst

Agenesis of corpus callosum, hypoplastic cerebellum, abnormal cerebrum, down slanting palpebral fissures, microphthalmia, micrognathia, thin distally placed thumbs, esophageal atresia, tracheo-esophageal fistula, C7 hemivertebrae, thoracic scoliosis, abnormal lung lobation, large left liver lobe, bilateral renal dysplasia with hydronephrosis and hydroureters, sacral dimple

None