Skip to main content

Table 1 Demographic and clinical characteristics of women with preterm birth before 35 weeks.

From: Polymorphisms in immunoregulatory genes and the risk of histologic chorioamnionitis in Caucasoid women: a case control study

Variable Histologic Chorio-amnionitis n = 69 No Histologic Chorio-amnionitis n = 112 Significant OR (95% CI), and Uncorrected P values
Maternal age (years) 29 (16–41) 30 (17–44)  
Delivery gestation (weeks) 28 (20–34) 30 (23–34) *
Mean birth weight 1399 (± 676) 1897 (± 504) < 0.0001
Maternal age ≥ 35 years 11 (16%) 18 (16%) ns
Maternal age ≤ 17 years 2 (3%) 2 (2%) ns
Any smoking 22 (31%) 29 (26%) ns
Any alcohol 44 (64%) 73 (65%) ns
Any substance use 7 (10%) 10 (9%) ns
Partner change for 14 (20%) 20 (18%) ns
pregnancy    
Cervical cerclage 3 (4%) 2 (2%) ns
Previous mid-trimester 4 (6%) 12 (11%) ns
miscarriage (12–20 weeks)    
2 or more preterm births 11 (16%) 20 (18%) ns
Placenta praevia after 22 weeks with bleeding 1 (1%) 2 (2%) ns
Documented clinical chorioamnionitis 22 (32%) 8 (7%) 6.1 (2.4–17), < 0.001
PPROM ≥ 3 hours 39 (57%) 74 (66%) ns
Gestation < 29 weeks 33 (48%) 12 (11%) 7.6 (3.4–18), < 0.001
Documented positive    
placental culture 10 (14%) 6 (5%) 3.0 (0.9–11), 0.04
Neonatal sepsis 10 (14%) 0 19 (3 – 823), < 0.001
Neonatal death 6 (9%) 3 (3%) ns
Post partum endometritis 5 (7%) 3 (3%) ns
  1. Descriptive statistical results are mean (± SD) or number (%) as appropriate, and maternal age and gestation as median (range). Characteristics are from index birth. PPROM = Preterm premature rupture of membranes 3 hours or more before delivery < 35 weeks.
  2. Univariate analyses were tested using Chi square analysis of 2 × 2 table, and uncorrected P values, Odds Ratio (OR), and 95% Confidence Intervals (CI), P values ≤ 0.05 are presented. Mean birth weights were tested by two-sample t-test, assuming unequal variances.
  3. * See Figure 1,
  4. ns, not significant.