Variable | Histologic Chorio-amnionitis n = 69 | No Histologic Chorio-amnionitis n = 112 | Significant OR (95% CI), and Uncorrected P values |
---|---|---|---|
Maternal age (years) | 29 (16–41) | 30 (17–44) |  |
Delivery gestation (weeks) | 28 (20–34) | 30 (23–34) | * |
Mean birth weight | 1399 (± 676) | 1897 (± 504) | < 0.0001 |
Maternal age ≥ 35 years | 11 (16%) | 18 (16%) | ns |
Maternal age ≤ 17 years | 2 (3%) | 2 (2%) | ns |
Any smoking | 22 (31%) | 29 (26%) | ns |
Any alcohol | 44 (64%) | 73 (65%) | ns |
Any substance use | 7 (10%) | 10 (9%) | ns |
Partner change for | 14 (20%) | 20 (18%) | ns |
pregnancy | Â | Â | Â |
Cervical cerclage | 3 (4%) | 2 (2%) | ns |
Previous mid-trimester | 4 (6%) | 12 (11%) | ns |
miscarriage (12–20 weeks) |  |  |  |
2 or more preterm births | 11 (16%) | 20 (18%) | ns |
Placenta praevia after 22 weeks with bleeding | 1 (1%) | 2 (2%) | ns |
Documented clinical chorioamnionitis | 22 (32%) | 8 (7%) | 6.1 (2.4–17), < 0.001 |
PPROM ≥ 3 hours | 39 (57%) | 74 (66%) | ns |
Gestation < 29 weeks | 33 (48%) | 12 (11%) | 7.6 (3.4–18), < 0.001 |
Documented positive | Â | Â | Â |
placental culture | 10 (14%) | 6 (5%) | 3.0 (0.9–11), 0.04 |
Neonatal sepsis | 10 (14%) | 0 | 19 (3 – 823), < 0.001 |
Neonatal death | 6 (9%) | 3 (3%) | ns |
Post partum endometritis | 5 (7%) | 3 (3%) | ns |