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Table 3 Percentage inhibition (%) of MLR-Bf significant IgG and its isotypes

From: Characterization of mixed lymphocyte reaction blocking antibodies (MLR-Bf) in human pregnancy

Different group of subjects Proportionate change in percentage inhibition of MLR-Bf significant IgG and its isotypes in terms of interquartile range (IQR)
  IgG IgG1 IgG2 IgG3 IgG4
  W × H (1:2) H × W (2:1) W × H (1:2) H × W (2:1) W × H (1:2) H × W (2:1) W × H (1:2) H × W (2:1) W × H (1:2) H × W (2:1)
Ist trimester 39 (35–67) 26 (21–63) 22 (18–28) 24 (15–26) 17 (-11–37) 21 (7–42) 68 (61–68) * 64 (60–63) * 19 (17–45) 17 (11–21)
IInd trimester 42 (28–71) 39 (35–64) 18 (15–24) 17 (14–19) 12 (3–33) 11 (9–15) 61 (63–70) * 62(61–67) * 29 (-14–33) 4 (-17–8)
IIIrd trimester 27 (21–62) 35 (27–67) -14 (-27–9) 13 (-8–27) 15 (9–23) 17 (14–21) 67 (61–82) * 71(62–76) * 15 (15–28) 13 (9–16)
Post delivery period 44 (20–68) 25 (23–68) 17 (-3–20) 15 (10–30) 5 (-9–19) 11 (7–31) 47 (14–47) 41(23–52) 8 (4–17) 11 (6–22)
Pre immunized RSA Women 34 (28–47) 28 (23–61) 6 (-12–9) -6 (-11–2) 2 (24–11) 5 (-22–7) 43 (17–37) 38(21–36) 6 (-12–6) 8 (5–19)
Post immunized RSA Women 51 (44–69) 60 (57–73) -7 (-16–7) 4 (-12–6) 12 (6–31) 21 (11–29) 67 (64–82) * 67(62–71) * 21 (19–26) 15 (10–30)
Healthy male -9 (-21–2) -17 (-8–4) -17 (-19–2) -8 (-11–3) -15 (-27–5) 4 (-17–2) -11 (-19–9) -12(-18–7) -6 (-29–4) -11 (-18–19)
Unmarried females -17 (-24–6) -23 (-35–2) -7 (-11–3) 3 (-7–10) -5 (-17–4) 9 (-21–12) 15 (-11–3) 12(-6–17) 14 (11–22) 25 (24–27)
  1. 1:2 (non irradiated cells of control female × irradiated cells of control male), 2:1 (non irradiated cells of control male × irradiated cells of control female) W = wife, H = husband. Values given in the table are calculated as percentage inhibition (%) against the base line measurement and shown as median and interquartile range(IQR), n = 10.*P < 0.001