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Table 2 Characteristics of patients with diagnosis of threatened abortion, premature labor or labor in relation to the presence or not of any ADR.

From: Drug therapy and adverse drug reactions to terbutaline in obstetric patients: a prospective cohort study in hospitalized women

 

With ADR (n = 25)

Without ADR (n = 89)

Significant level

Age (yr., mean ± SD)

28.8 ± 5.9

25.6 ± 6.0

p = 0.02

DIAGNOSIS

   

Threatened abortion

4(16%)

23 (25.8%)

 

Premature labor

20 (80%)

28(31.5%)

<0.001

Labor

1 (4%)

38 (42.7%)

 

HOSPITAL STAY (days)

   

≤ 3

20 (80%)

45 (50.6%)

p= 0.016

>3

5 (20%)

44 (49.4%)

 

DRUGS/DAY × PATIENT -1

   

Mean ± SD

3.3 ± 1.3

4.4 ± 2.2

p = 0.02

UTERINE INHIBITOR

   

a) Terbutaline

24 (96%)

19(21.3%)

 

b) Indomethacin

1 (4%)

35 (40.4%)

p < 0.001

c) None

-

34 (38.3%)

 

TERBUTALINE DOSE (mg/day)

)

  

Mean ± SD

13.0 ± 3.5

14.5 ± 2.2

p > 0.05

Range

5–15

5–15