Prevention of gestational diabetes through lifestyle intervention: study design and methods of a Finnish randomized controlled multicenter trial (RADIEL)

Table 1 Data collection in The Finnish Gestational Diabetes Prevention Study (RADIEL)

	Enrollment	Prepregnancy follow-up every 3 months	1st trimester	2nd trimester	3rd trimester	Birth	6 weeks after delivery	6 months after delivery	12 months after delivery
Questionnaires
Background- and progress questionnaires
Socioeconomic status	X						X
Medical and obstetric history	X
Self reported morbidity and use of medication	X	X	X	X	X		X	X	X
Smoking and alcohol consumption	X	X	X	X	X		X	X	X
Quality of life	X	X	X	X	X		X	X	X
Diet	X	X	X	X	X		X	X	X
Physical activity	X	X	X	X	X		X	X	X
EPDS	X		X				X	X	X
15D	X		X	X	X		X	X	X
Logbooks for food and physical activity	X		X		X				X
Physical measurements
Height	X
Weight and BMI	X	X	X	X	X		X	X	X
Waist-hip ratio	X	X					X	X	X
Resting blood pressure and heart rate	X	X	X	X	X		X	X	X
Laboratory tests
75 g 2-hour OGTT	X		X	X			X		X
Glucose, insulin, GHbA_1c and hsCRP	X	X	X	X	X		X	X	X
ALAT, lipids	X						X		X
TSH and free T4	X						X
DNA	X
Spare blood for further analyses	X	X	X	X	X		X	X	X
Offspring
Birth weight and length						X
Apgar score						X
Cord-blood gas analysis (pH)						X
Cord-blood sample (DNA)						X

EPDS = Edinburgh Postnatal Depression Scale; BMI = body mass index; OGTT = oral glucose tolerance test; GHbA_1c = glycated hemoglobin; hsCRP = high sensivity C-reactive protein; ALAT = alanin transaminase; TSH = thyroid-stimulating hormone; T4 = thyroxin.

ISSN: 1471-2393