|
Variable
|
Cutoff1
|
DR1
|
Cutoff2
|
DR2
|
Area
|
SE
|
p-value
|
95% CI
|
|---|
|
BMI, kg/m2
|
23.6
|
37.5
|
24.3
|
25
|
0.769
|
0.086
|
0.010
|
0.600
|
0.937
|
|
PAPP-A, MoM
|
0.58
|
50
|
0.49
|
50
|
0.707
|
0.116
|
0.046
|
0.480
|
0.935
|
|
Inhibin A, MoM
|
1.76
|
50
|
2.18
|
50
|
0.780
|
0.095
|
0.007
|
0.593
|
0.967
|
|
sFlt-11, (pg/ml)
|
2358
|
75
|
3064
|
25
|
0.842
|
0.080
|
0.001
|
0.686
|
0.998
|
|
sFlt-12
|
4680
|
75
|
6040
|
50
|
0.944
|
0.020
|
<0.001
|
0.906
|
0.983
|
|
PlGF1, (pg/ml)
|
257
|
62.5
|
200
|
37.5
|
0.751
|
0.103
|
0.016
|
0.549
|
0.953
|
|
PlGF2
|
113.4
|
50
|
86.5
|
37.5
|
0.847
|
0.060
|
0.001
|
0.729
|
0.965
|
|
sFlt-1/PlGF1
|
6.05
|
75
|
7.0
|
75
|
0.851
|
0.092
|
0.001
|
0.670
|
1.000
|
|
sFlt-1/PlGF2
|
28.2
|
87.5
|
43.7
|
50
|
0.939
|
0.033
|
<0.001
|
0.873
|
1.000
|
- Cutoff1: cutoff value at a fixed FPR of 10%, DR1: DR at a fixed FPR of 10%, Cutoff2: cutoff value at a fixed FPR of 5%, DR2: DR at a fixed FPR of 5%, PAPP-A: pregnancy-associated plasma protein-A, sFlt-11: second trimester sFlt-1, PlGF1: second trimester PlGF, sFlt-1/PlGF1: second trimester sFlt-1/PlGF ratio, sFlt-12: third trimester sFlt-1, PlGF2: third trimester PlGF, sFlt-1/PlGF2: third trimester sFlt-1/PlGF ratio, SE: standard error.
