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Table 2 Distributions of the variables of interest

From: Screening models using multiple markers for early detection of late-onset preeclampsia in low-risk pregnancy

variable Preeclampsia (n = 8) Unaffected group (n = 254) P value
Median gestational age (weeks) 11 (10–13) 11 (10–13) 0.651
PAPP-A, MoM 0.63 (0.34–1.67) 1.00 (0.20–3.85) 0.046
NT, MoM 1.05 (0.81–1.28) 1.00 (0.45–1.99) 0.724
Median gestational age 16 (15–17) 16 (14–18) 0.784
MSAFP, MoM 1.00 (0.41–4.38) 1.10 (0.55–2,96) 0.550
hCG,MoM 1.66 (1.16–2.68) 1.00 (0.20–6.53) 0.001
uE3, MoM 0.97 (0.69–1.28) 1.00 (0.46–1.83) 0.521
Inhibin A, MoM 1.86(0.82–2.96) 1.00 (0.39–3.676) 0.007
Median gestational age 26 (24–27) 27 (25–27) 0.378
sFlt-11, (pg/ml) 2360 (932–4435) 1296 (166–5710) 0.001
PlGF1, (pg/ml) 219 (34.25–698) 491 (91.37–2243) 0.016
sFlt-1/PlGF1 11.9 (1.7–70.9) 2.6 (0.3–12) 0.001
Median gestational age 34 (34–36) 36 (34–37) <0.001
sFlt-12, (pg/ml) 6275 (4307–12835) 2334 (71.61–50475) <0.001
PlGF2, (pg/ml) 115.9 (16.48–284.9) 287.95 (6.60–1749) 0.001
sFlt-1/PlGF2 76.3 (15.1–352.7) 8 (0.8–156) <0.001
Uterine artery doppler    
Mean RI 0.55 (0.48–0.77) 0.57 (0.37–0.83) 0.972
Mean PI 0.94 (0.71–1.86) 0.97 (0.52–2.00) 0.949
Mean SD 2.25 (1.95–4.25) 2.35 (1.47–5.91) 0.913
Highest RI 0.58 (0.53–0.77) 0.62 (0.38–0.88) 0.526
Highest PI 1.03 (0.79–1.86) 1.06 (0.54–2.76) 0.808
Highest SD 2.40 (2.10–4.30) 2.58 (1.63–8.58) 0.642
Notch (%) 0.4 12.5 0.072
  1. Data are expressed as median (minimum–maximum).
  2. PAPP-A: pregnancy-associated plasma protein-A, NT: nuchal translucency thickness, MSAFP: alpha-fetoprotein, hCG: human chorionic gonadotropin, uE3: unconjugated estriol, sFlt-11: second trimester sFlt-1, PlGF1: second trimester PlGF, sFlt-1/PlGF1: second trimester sFlt-1/PlGF ratio, sFlt-12: third trimester sFlt-1, PlGF2: third trimester PlGF, sFlt-1/PlGF2: thirst trimester sFlt-1/PlGF ratio.