Table 2 Distributions of the variables of interest

Median gestational age (weeks)

11 (10–13)

11 (10–13)

0.651

PAPP-A, MoM

0.63 (0.34–1.67)

1.00 (0.20–3.85)

0.046

NT, MoM

1.05 (0.81–1.28)

1.00 (0.45–1.99)

0.724

Median gestational age

16 (15–17)

16 (14–18)

0.784

MSAFP, MoM

1.00 (0.41–4.38)

1.10 (0.55–2,96)

0.550

hCG,MoM

1.66 (1.16–2.68)

1.00 (0.20–6.53)

0.001

uE3, MoM

0.97 (0.69–1.28)

1.00 (0.46–1.83)

0.521

Inhibin A, MoM

1.86(0.82–2.96)

1.00 (0.39–3.676)

0.007

Median gestational age

26 (24–27)

27 (25–27)

0.378

sFlt-1¹, (pg/ml)

2360 (932–4435)

1296 (166–5710)

0.001

PlGF¹, (pg/ml)

219 (34.25–698)

491 (91.37–2243)

0.016

sFlt-1/PlGF¹

11.9 (1.7–70.9)

2.6 (0.3–12)

0.001

Median gestational age

34 (34–36)

36 (34–37)

<0.001

sFlt-1², (pg/ml)

6275 (4307–12835)

2334 (71.61–50475)

<0.001

PlGF², (pg/ml)

115.9 (16.48–284.9)

287.95 (6.60–1749)

0.001

sFlt-1/PlGF²

76.3 (15.1–352.7)

8 (0.8–156)

<0.001

Uterine artery doppler

Mean RI

0.55 (0.48–0.77)

0.57 (0.37–0.83)

0.972

Mean PI

0.94 (0.71–1.86)

0.97 (0.52–2.00)

0.949

Mean SD

2.25 (1.95–4.25)

2.35 (1.47–5.91)

0.913

Highest RI

0.58 (0.53–0.77)

0.62 (0.38–0.88)

0.526

Highest PI

1.03 (0.79–1.86)

1.06 (0.54–2.76)

0.808

Highest SD

2.40 (2.10–4.30)

2.58 (1.63–8.58)

0.642

Notch (%)

0.4

12.5

0.072