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Table 1 Criteria contributing to suspicion of clinical diagnosis of preeclampsia*

From: Multicenter prospective clinical study to evaluate the prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS): study protocol

Clinical signs and symptoms

a. New onset of elevated blood pressurea

b. Aggravation of pre-existing hypertension

c. New onset of protein in urineb

d. Aggravation of pre-existing proteinuria

e. One or more other reason(s) for clinical suspicion of preeclampsia (see i. and ii.)

i. Preeclampsia-related symptoms:

1. Epigastric pain

2. Excessive edema/severe swelling, (face, hands, feet)

3. Headache

4. Visual disturbances

5. Sudden weight gain (>1 kg/week in the third trimester)

ii. Preeclampsia-relatedfindings:

1. Low platelets

2. Elevated liver transaminases

3. (Suspected) intrauterine growth restriction

4. Abnormal uterine perfusion detected by Doppler sonography with mean pulsatility index >95th percentile in the second trimester and/or bilateral uterine artery notching

  1. aDoes not need to be defined hypertension (≥140 mmHg systolic and/or ≥90 mmHg diastolic).
  2. bDoes not need to be defined proteinuria – any protein in the urine is sufficient.
  3. *The presence of at least one of these clinical criteria for suspicion of preeclampsia is required for inclusion in the study.