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Table 3 Impact of prepregnancy obesity on pregnancy and neonatal outcomes (n = 2009)

From: Socioeconomic disparities in prepregnancy BMI and impact on maternal and neonatal outcomes and postpartum weight retention: the EFHL longitudinal birth cohort study

Outcome

Frequency (%)

Adjusted ORa(95% CI)

p-value (2-sided)

Obstetric Complication:

Hyperglycaemia

   

  Normal weight

65 (8.0%)

Reference

 

  Underweight

5 (3.7%)

0.532 (0.207 – 1.371)

0.192

  Overweight

35 (9.7%)

1.210 (0.754 – 1.940)

0.430

  Obesity

38 (11.8%)

1.464 (0.921 – 2.328)

0.107

  Missingb

382

 

Trendc (0.024*)

Gestational diabetes

   

  Normal weight

21 (2.4%)

Reference

 

  Underweight

0 (0%)

—

—

  Overweight

7 (2.0%)

1.040 (0.396 – 2.732)

0.937

  Obesity

11 (3.6%)

2.327 (1.037 – 5.223)

0.041*

  Missing

337

Preeclampsia

   

  Normal weight

25 (3.1%)

Reference

 

  Underweight

0 (0%)

—

—

  Overweight

11 (3.3%)

1.184 (0.559 – 2.505)

0.660

  Obesity

29 (9.8%)

3.143 (1.694 – 5.830)

< 0.001*

  Missing

430

  

Cesarean delivery

   

  Normal weight

238 (23.0%)

Reference

 

  Underweight

38 (23.0%)

0.950 (0.588 – 1.536)

0.834

  Overweight

146 (34.4%)

1.802 (1.349 – 2.409)

<0.001*

  Obesity

127 (35.9%)

2.229 (1.646 – 3.018)

<0.001*

  Missing

32

 

Trend (< 0.001*)

Neonatal Complication:

Intensive/Special care admission

   

  Normal weight

117 (11.3%)

Reference

 

  Underweight

15 (9.1%)

0.590 (0.296 – 1.176)

0.134

  Overweight

67 (15.9%)

1.339 (0.921 – 1.947)

0.126

  Obesity

73 (20.6%)

1.839 (1.269 – 2.665)

0.001*

  Missing

36

 

Trend (<0.001*)

Fetal distress

   

  Normal weight

62 (6.7%)

Reference

 

  Underweight

17 (11.3%)

2.178 (1.147 – 4.133)

0.017*

  Overweight

24 (6.0%)

1.222 (0.706 – 2.113)

0.474

  Obesity

33 (9.6%)

1.870 (1.103 – 3.169)

0.020*

  Missing

191

 

Trend (0.143)

Jaundice

   

  Normal weight

39 (4.8%)

Reference

 

  Underweight

11 (8.2%)

1.782 (0.821 – 3.866)

0.144

  Overweight

30 (8.4%)

1.762 (1.017 – 3.053)

0.044*

  Obesity

22 (6.8%)

1.592 (0.882 – 2.872)

0.123

  Missing

382

 

Trend (0.163)

Respiratory distress

   

  Normal weight

38 (4.7%)

Reference

 

  Underweight

6 (4.5%)

0.879 (0.332 – 2.330)

0.796

  Overweight

20 (5.6%)

1.275 (0.700 – 2.322)

0.427

  Obesity

22 (6.8%)

1.294 (0.700 – 2.394)

0.411

  Missing

382

 

Trend (0.288)

Congenital anomaly

   

  Normal weight

62 (7.3%)

Reference

 

  Underweight

10 (7.3%)

1.362 (0.662 – 2.804)

0.401

  Overweight

26 (7.1%)

0.966 (0.559 – 1.668)

0.901

  Obesity

25 (7.9%)

1.179 (0.692 – 2.011)

0.544

  Missing

343

 

Trend (0.868)

Macrosomia (birthweight >4kg)

   

  Normal weight

140 (13.6%)

Reference

 

  Underweight

10 (6.2%)

0.389 (0.176 – 0.859)

0.019*

  Overweight

70 (16.5%)

1.334 (0.945 – 1.884)

0.101

  Obesity

93 (26.3%)

2.262 (1.619 – 3.160)

< 0.001*

  Missing

43

 

Trend (< 0.001*)

Resuscitation

   

  Normal weight

253 (26.1%)

Reference

 

  Underweight

32 (20.9%)

0.675 (0.417 – 1.091)

0.108

  Overweight

112 (27.8%)

1.186 (0.887 – 1.587)

0.248

  Obesity

118 (34.5%)

1.499 (1.109 – 2.024)

0.009*

  Missing

143

 

Trend (0.001*)

  1. *Significant at the 0.05 level.
  2. aAdjusted for maternal age, employment (categorical) and education, marital status (categorical), paternal employment (categorical) and education, household ownership, number of children under 16, alcohol intake and smoking status during pregnancy, maternal non-medical drug use, primiparity, pre-existing hypertension, and year of recruitment.
  3. bDue to differences in hospital perinatal data collection among participating hospitals, some maternal morbidities have more missing data.
  4. c p-value for linear trend of adjusted ORs.