Prediction of preeclampsia and induced delivery at <34 weeks gestation by sFLT-1 and PlGF in patients with abnormal midtrimester uterine Doppler velocimetry: a prospective cohort analysis

Table 2 Maternal serum PlGF and sFLT-1 levels and their ratio

	PE (n = 12)	No PE (n = 38)	P-value^a	Others (n = 16) (Uncomplicated)	GH (n = 16)	P-value^b	Normotensive IUGR (n = 6)	P-value^c	Delivery < 34 weeks (n = 7)	Delivery ≥ 34 weeks (n = 44)	P-value^d
PlGF (pg/mL)	105.6 (70.7-248.7)	218.5 (131.2-322.5)	0.041	274.6 (157.9-413.6)	198.7 (91.5-305.3)	0.142	165.9 (72.1-220.7)	0.033	75.1 (64.6-131.7)	221.7 (117.4-336.4)	0.003
sFLT-1 (pg/mL)	1879.0 (1379.5-2168.3)	1144.0 (842.2-1882.8)	0.046	1458.0 (1018.8-1896.3)	1032.6 (826.8-1649.8)	0.258	1324.4 (673.1-2012.0)	0.768	2158.0 (1858.0-3463.0)	1298.0 (846.1-1876.0)	0.008
sFLT-1/PlGF ratio	18.8 (4.8-29.1)	6.2 (3.4-8.8)	0.022	5.9 (2.9-8.6)	5.9 (3.6-9.1)	0.366	8.6 (4.0-19.6)	0.161	29.4 (14.1-53.9)	6.0 (3.4-9.0)	0.001

Data are given as median (interquartile range).
^a Mann–Whitney statistical test comparing PE vs No PE.
^b Mann–Whitney statistical test comparing GH vs Others.
^c Mann–Whitney statistical test comparing IUGR vs Others.
^d Mann–Whitney statistical test comparing delivery < 34 weeks vs delivery ≥ 34 weeks.
PE = Preeclampsia, GH = Gestational hypertension, IUGR = Intrauterine growth restriction.

ISSN: 1471-2393