Table 1 Maternal and foetal characteristics of the study population
Characteristic | All patients (n = 50) | PE (n = 12) | IUGR (n = 6)# | GH (n = 16) | Others (n = 16) | P-value |
|---|---|---|---|---|---|---|
Age, y | ||||||
Mean ± SD | 29.7 ± 4.9 | 29.8 ± 3.9 | 33.3 ± 4.8 | 28.3 ± 3.6 | 29.6 ± 6.3 | 0.206* |
Minimum - maximum | 19 - 40 | 24 - 38 | 28 - 40 | 22 - 34 | 19 - 39 | |
Gravidity | 0.613** | |||||
Median | 1 | 1 | 2 | 1 | 2 | |
Minimum - maximum | 1 - 9 | 1 - 9 | 1 - 8 | 1 - 5 | 1 - 5 | |
Parity | 0.612** | |||||
Median | 0 | 0 | 0 | 0 | 0 | |
Minimum - maximum | 0 - 5 | 0 - 4 | 0 - 5 | 0 - 2 | 0 - 1 | |
Body mass index (pregravid), kg/m 2 | 0.132* | |||||
Mean ± SD | 27.1 ± 8.2 | 30.6 ± 8.0 | 21.7 ± 3.2 | 28.1 ± 9.1 | 25.6 ± 6.3 | |
Minimum - maximum | 14.5 - 47.0 | 19.8 - 45.0 | 18.7 - 27.3 | 14.5 - 45.7 | 18.8 - 47.0 | |
Chronic hypertension, n (%) | 8 (16.0%) | 4 (33.3%) | 0 (0.0%) | 4 (25.0%) | 0 (0.0%) | 0.049*** |
Thrombophilia, n (%) | 5 (10.0%) | 0 (0.0%) | 0 (0.0%) | 3 (18.8%) | 2 (12.5%) | 0.755*** |
Nicotine abuse, n (%) | 14 (28.0%) | 5 (41.7%) | 1 (16.7%) | 6 (37.5%) | 2 (12.5%) | 0.238*** |
Highest systolic blood pressure, mmHg | < 0.001* | |||||
Mean ± SD | 143.2 ± 23.1 | 165.8 ± 21.2 | 128.7 ± 5.4 | 149.4 ± 20.0 | 124.7 ± 9.9 | |
Minimum - maximum | 110 - 200 | 140 - 200 | 120 - 135 | 130 - 200 | 110 - 140 | |
Highest diastolic blood pressure, mmHg | < 0.001* | |||||
Mean ± SD | 90.4 ± 17.6 | 110.5 ± 13.4 | 79.7 ± 6.2 | 91.8 ± 15.9 | 77.3 ± 7.1 | |
Minimum - maximum | 60 - 130 | 90 - 130 | 70 - 86 | 60 - 124 | 60 - 90 | |
Proteinuria, mg/d | ||||||
Mean ± SD | 1180 ± 2524 | 2613 ± 3394 | n.a. | 157 ± 196 | n.a. | |
Minimum - maximum | 0 - 9986 | 109 - 9986 | n.a. | 0 - 283 | n.a. | |
Placenta weight, g | 0.129* | |||||
Mean ± SD | 324 ± 98 | 300 ± 86 | 322 ± 29 | 286 ± 145 | 443 ± 71 | |
Minimum - maximum | 124 - 510 | 182 - 461 | 283 - 364 | 124 - 476 | 369 - 510 | |
Amnion fluid index (AFI), n (%) | 0.839*** | |||||
Oligohydramnion (AFI ≤ 8) | 13 (26.0%) | 3 (25.0%) | 2 (33.3%) | 4 (25.0%) | 4 (25.0%) | |
Polyhydramnion (AFI > 18) | 7 (14.0%) | 3 (25.0%) | 1 (16.7%) | 1 (6.3%) | 2 (12.5%) | |
Birth weight, g | < 0.001* | |||||
Mean ± SD | 2588 ± 809 | 1859 ± 658 | 2270 ± 303 | 2588 ± 750 | 3175 ± 626 | |
Minimum - maximum | 620 - 3940 | 890 - 2980 | 1750 - 2620 | 620 - 3610 | 1860 - 3940 | |
Percentile of birth weight, n (%) | ||||||
SGA (<10th centile) | 16 (32.0%) | 5 (41.7%) | 6 (100.0%) | 6 (37.5%) | 0 (0.0%) | |
LGA (>90th centile) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |
5´-APGAR-Score | 0.398** | |||||
Median | 10 | 9 | 10 | 10 | 10 | |
Minimum - maximum | 8 - 10 | 8 - 10 | 9 - 10 | 8 - 10 | 9 - 10 | |
Induction of lung maturation, n (%) | 13 (26.0%) | 4 (33.3%) | 6 (100.0%) | 2 (12.5%) | 1 (6.3%) | 0.019*** |
Newborns < 34 + 0 weeks, n (%) | 7 (14.0%) | 5 (41.7%) | 0 (0.0%) | 2 (12.5%) | 0 (0.0%) | 0.008*** |
Gestational age at delivery, weeks + days | 0.009** | |||||
Mean (w + d) ± SD (d) | 37 + 2 ± 24 | 34 + 4 ± 26 | 37 + 5 ± 5 | 37 + 4 ± 25 | 38 + 6 ± 17 | |
Minimum - maximum | 26 + 4 - 42 + 0 | 27 + 4 - 40 + 3 | 36 + 5 - 39 + 0 | 26 + 2 – 41 + 0 | 34 + 1 - 42 + 0 |