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Table 2 Perinatal/neonatal, 18–24 months, and 5-year outcomes of infants/children by gestational age at delivery

From: Association between gestational age at birth, antenatal corticosteroids, and outcomes at 5 years: multiple courses of antenatal corticosteroids for preterm birth study at 5 years of age (MACS-5)

Outcomes Preterm (<30 weeks) N = 200 Preterm (30–36 weeks) N = 1066 Term (≥37 weeks) N = 462a
Genderb    
Male 106 (53%) 560 (53%) 240 (52%)
Female 94 (47%) 506 (47%) 222 (48%)
Death or serious neonatal morbidity: composite primary outcome (one or more of death, severe RDSc, BPDd, IVHe [grade III/IV], cystic PVLf, NECg) 126 (64%) 107 (10%) 2 (<0.01%)
Missing 0 (0%) 0 (0%) 1 (<0.01%)
Death or neurologic impairment at 18–24 months: composite primary outcome (one or more of death, cerebral palsy or cognitive delay) 89 (45%) 128 (12.0%) 27 (6%)
Missing 1 (0.01%) 5 (0.1%) 2 (<0.01%)
Death or severe disability (neuromotor, neurosensory, neurocognitive) at 5 years § 104 (52%) 237 (22%) 86 (19%)
  1. a1 lost to follow-up case earlier in trial found and included at 5 years; no neonatal and 18–24 months data available;
  2. bNew information found on gender.
  3. cRDS = respiratory distress syndrome; dBPD = bronchopulmonary dysplasia;
  4. eIVH = intraventricular hemorrhage; fPVL = periventricular leukomalacia;
  5. gNEC = necrotising enterocolitis.
  6. §Clinical information of 19 cases missing/inadequate questionnaires were reviewed by an adjudication committee (10 cases were adjudicated to contribute to analysis and primary outcome; 9 had insufficient information).