From: Mode of delivery and postpartum HIV-1 disease progression and mortality in a Kenyan cohort
Charateristics | Vaginal delivery (nā=ā405) | Non-scheduled cesarean section (nā=ā74) | P (NSCS vs. VD)a | Scheduled cesarean section (nā=ā22) | P (SCS vs. VD)a |
---|---|---|---|---|---|
Ā | Mean (95% CI) or % (n) | Mean (95% CI) or % (n) | Ā | Mean (95% CI) or % (n) | Ā |
Age at enrollment (yr) | 25.1 (24.6, 25.5) | 25.8 (24.8, 26.9) | 0.2 | 27.8 (25.7, 29.9) | 0.006 |
Prenatal weight (kg) | 63.5 (62.6, 64.4) | 62.9 (61.0, 62.7) | 0.6 | 70.4 (65.1, 75.7) | 0.001 |
Prior Pregnancies | 1.5 (1.4, 1.6) | 1.4 (1.1, 1.7) | 0.5 | 1.9 (1.1, 2.7) | 0.1 |
Gestational Age (wk) | 39.2 (39.0, 39.4) | 39.7 (39.3, 40.2) | 0.03 | 38.4 (37.1, 39.7) | 0.2 |
Years of Education | 8.9 (8.6, 9.2) | 8.9 (8.3, 9.6) | 0.9 | 9.6 (8.7, 10.5) | 0.2 |
Lifetime Sexual Partners | 3.1 (2.9, 3.3) | 5.0 (2.0, 7.9) | 0.2 | 3.4 (2.4, 4.4) | 0.5 |
Years in Relationship | 4.8 (4.4, 5.2) | 5.7 (4.5, 7.0) | 0.7 | 6.8 (3.9, 9.6) | 0.2 |
Stable partnership | 97% (382/394) | 85% (62/73) | <0.001 | 86% (19/22) | 0.04 |
Employed | 29% (113/394) | 37% (27/73) | 0.2 | 55% (12/22) | 0.01 |
Length of Labor (hrs) | 9.8 (9.2, 10.3) | 11.9 (9.9, 13.8) | 0.04 | N/A | Ā |
Duration of Rupture of Membranes (hrs) | 4.5 (3.2, 5.9) | 6.5 (3.9, 9.0) | 0.2 | N/A | Ā |
Doses of zidovudine | 2.8 (2.6, 3.0) | 3.7 (3.1, 4.3) | 0.004 | 2.5 (1.8, 3.2) | 0.5 |
Antenatal BMI | 24.5 (24.2, 24.8) | 25.0 (24.4, 25.6) | 0.2 | 27.0 (25.1, 28.8) | <0.001 |
Antenatal Hgb | 10.5 (10.3, 10.7) | 10.5 (10.2, 10.8) | 1.0 | 10.9 (10.5, 11.3) | 0.2 |
Antenatal CD4 count | 486.6 (460.4, 512.7) | 418.9 (363.4, 474.4) | 0.04 | 456.1 (371.5, 540.7) | 0.6 |
Antenatal HIV-1 RNA log10 copies/ml | 4.6 (4.5, 4.7) | 4.8 (4.6, 5.0) | 0.05 | 4.7 (4.4, 5.0) | 0.7 |
Delivery HIV-1 RNA log10 copies/ml | 4.0 (3.9, 4.1) | 4.1 (3.9, 4.4) | 0.5 | 3.6 (3.2, 4.1) | 0.06 |