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Table 1 Summary measures of psychotropic prescription drug use before, during and after pregnancy

From: Patterns of psychotropic medicine use in pregnancy in the United States from 2006 to 2011 among women with private insurance

N = 343299 6 months preconcept n (%) 1st trimester n (%) 2nd trimester n (%) 3rd trimester n (%) Pregnancy total n (%) Pregnancy total with >1 Rx n (%)
Any psychotropic 33,995 (9.9) 24776 (7.2) 15883 (4.6) 18161 (5.3) 35303 (10.3) 23261 (6.8)
Antidepressant 23,083 (6.7) 17214 (5.0) 12235 (3.6) 11937 (3.5) 22275 (6.5) 15097 (4.4)
 SSRI 16524 (4.8) 12881 (3.8) 9773 (2.9) 9751 (2.8) 17410 (5.1) 12278 (3.6)
 SNRI 3170 (0.9) 2175 (0.6) 973 (0.3) 805 (0.2) 2382 (0.8) 1075 (0.3)
 Tricyclic 1222 (0.4) 611 (0.2) 236 (0.07) 209 (0.06) 784 (0.2) 308 (0.1)
 Other 4390 (1.3) 3085 (0.9) 1875 (0.6) 1634 (0.5) 4019 (1.2) 1026 (0.3)
 ≥ 2 antidepressants 2776 (0.8) 2132 (0.6) 889 (0.3) 676 (0.2) 3521 (1.0) 1613 (0.5)
Anxiolytic 12969 (3.8) 7503 (2.2) 3881 (1.1) 7002 (2.0) 14535 (4.2) 9235 (2.7)
 Benzo or benzo-like* 12231 (3.5) 6840 (2.0) 3391 (1.0) 6686 (2.0) 13486 (3.9) 8613 (2.5)
 Other 950 (0.3) 809 (0.2) 549 (0.2) 377 (0.1) 1375 (0.4) 757 (0.2)
Antipsychotic 1344 (0.4) 1728 (0.5) 808 (0.2) 503 (0.1) 2373 (1.1) 1015 (0.3)
 Atypical 899 (0.3) 604 (0.2) 315 (0.1) 301 (0.1) 742 (0.2) 388 (0.1)
 Typical 357 (0.1) 1072 (0.3) 464 (0.1) 160 (0.05) 1573 (0.5) 995 (0.3)
Stimulant/ADHD 2798 (0.8) 1982 (0.6) 498 (0.1) 325 (0.1) 2062 (0.6) 545 (0.2)
 ≥ 2 categories of psychotropic** 5423 (1.6) 3339 (1.0) 1431 (0.4) 1519 (0.5) 5423 (1.6) 2390 (0.7)
 Antidepressant + anxiolytic 4195 (1.2) 2293 (0.7) 1064 (0.3) 1247 (0.36) 4068 (1.2) 1630 (0.5)
  1. *Includes benzodiazepines as well as eszopliclone, zolpiedem, and zaleplon.
  2. **defined as prescriptions for ≥ 1 class of psychotropic medicine during pregnancy e.g. a benzodiazepine and an antidepressant; does not include women who used ≥ 1 medicine within the same class (e.g. two antidepressants).