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Table 2 Diagnostic indices of the C/B ratio in predicting Hb Bart’s disease (using 45% as a cut-off point; Area under curve 0.929)

From: Screening for hemoglobin Bart’s disease among fetuses at risk at mid-pregnancy using the fetal cardiac diameter to biparietal diameter ratio

 

Hb Bart’s disease

Normal

Total

Abnormal CB ratio

32

19

51

Normal CB ratio

3

66

69

Total

35

85

120

  1. Sensitivity: 91.43% (32/35) 95% CI: 82.20 - 100.7%.
  2. Specificity: 77.65% (66/85) 95% CI: 68.80 - 86.5%.
  3. Positive predictive accuracy: 62.70% (32/51) 95% CI: 49.50 – 76.00%.
  4. Negative predictive accuracy: 95.770% (66/69) 95% CI: 90.1 - 101.2%.