Table 4 Summary of study results for women with suspected membrane rupture; women with unknown membrane status upon entry to the study but who had a suspected membrane rupture
Study | N | TP | FN | TN | FP | Sensitivity% (CI) | Specificity% (CI) | PPV% (CI) | NPV% (CI) |
|---|---|---|---|---|---|---|---|---|---|
Albayrak 2011 [61] | 167 | 79 | 9 | 77 | 2 | 89.8 (81 0–94.9) | 97.5 (90.3–99.6) | 97.5 (90.5–99.6) | 89.5 (80.6–94.8) |
Tagore 2010 [59] | 94 | 35 | 5 | 51 | 3 | 87.5 (72.4–95.3) | 94.4 (83.7–98.6) | 92.1 (77.5–97.9) | 91.1 (79.6–96.7) |
Martinez de Tejada 2006 [52] | 49 | 19 | 3 | 20 | 7 | 86.4 (64.0–96.4) | 74.1 (53.4–88.1) | 73.1 (51.9–87.6) | 87.0 (65.3–96.6) |
Kubota 1998 [46] | 48 | 18 | 1 | 27 | 2 | 94.7 (71.9–99.7) | 93.1 (75.8–98.8) | 90.0 (66.9–98.2) | 96.4 (79.8–99.8) |
Jain 1998 [49] | 100 | 25 | 0 | 67 | 8 | 100 (83.4–100) | 89.3 (79.5–94.9) | 75.8 (57.4–88.3) | 100 (93.2–100) |
Ragosch 1996 [50] | 75 | 35 | 0 | 33 | 7 | 100 (87.7–100) | 82.5 (66.6–92.1) | 83.3 (68.0–92.5) | 100 (87.0–100) |
Actim® PROM pooled | 533 | 211 | 18 | 275 | 29 | 92.1 (87.7–95.1) | 90.5 (86.4–93.4) | 87.9 (82.9–91.6) | 93.9 (90.3–96.2) |
Birkenmaier 2012 [57] | 199 | 51 | 3 | 143 | 2 | 94.4 (83.7–98.6) | 98.6 (94.6–99.8) | 96.2 (85.9–99.3) | 97.9 (93.6–99.5) |
Albayrak 2011 [61] | 167 | 83 | 5 | 77 | 2 | 94.3 (86.6–97.9) | 97.5 (90.3–99.6) | 97.6 (91.0–99.6) | 93.9 (85.7–97.7) |
Tagore 2010 [59] | 100 | 38 | 3 | 59 | 0 | 92.7 (79.0–98.1) | 100 (92.4–100) | 100 (88.6–100) | 95.2 (85.6–98.7) |
Lee 2007 [56] | 183 | 157 | 2 | 21 | 3 | 98.7 (95.1–99.8) | 87.5 (66.5–96.7) | 98.1 (94.2–99.5) | 91.3 (70.5–98.5) |
Cousins 2005 [55] | 203 | 90 | 1 | 112 | 0 | 98.9 (93.2–99.9) | 100 (95.9–100) | 100 (94.9–100) | 99.1 (94.4–99.95) |
AmniSure® pooled | 852 | 419 | 14 | 412 | 7 | 96.8 (94.5–98.1) | 98.3 (96.4–99.3) | 98.4 (96.5–99.3) | 96.7 (94.4–98.1) |