Differential levels of amino acid transporters System L and ASCT2, and the mTOR protein in placenta of preeclampsia and IUGR

Table 1 Characteristic averages of pregnancy groups

	Full term control	Preterm control	Preeclampsia	IUGR
Maternal age	31.0 ± 6.4	31.0 ± 4.9	34.0 ± 4.3	31.6 ± 6.0
Maternal BMI (kg/m2)	21.3 ± 6.6	20.0 ± 3.7	23.8 ± 5.0	17.8 ± 1.2
Percent nulliparous	70	30	30	70
Blood pressure at delivery (mmHg)
Systolic (mmHg)	121 ± 9	116 ± 7	162 ± 19 ^a	122 ± 24
Diastolic (mmHg)	73 ± 9	66 ± 10	97 ± 10^c	77 ± 22^d
Blood pressure <20 weeks GA
Systolic (mmHg)	118 ± 7	109 ± 6	141 ± 11	105 ± 21
Diastolic (mmHg)	77 ± 11	59 ± 10	87 ± 6	64 ± 12
Gestational weeks at delivery	39.2 ± 1.5	34.4 ± 0.7	33.6 ± 2.0^a	34.5 ± 3.1^a
Birth weight (g)	2835 ± 435	1993 ± 236	1446 ± 333^a	1465 ± 335^a
Birth weight centile	35.8 ± 25.1	30.4 ± 19.8	5.2 ± 7.3^a	2.6 ± 3.6^a
Placental weight (g)	558 ± 141	448 ± 122	348 ± 91^b	332 ± 82^a
Smoking (%)	0	10	0	10
Ceasarean delivery (%)	90	30	80	60

Continuous variables are shown as mean ± s.d. Dichotomous variables are given as a percentage. Smoking status was self-reported. BMI, body mass index; BP, blood pressure; n =10 samples/case condition.
^a P value < 0.0001 (Full term control vs Preeclampsia, IUGR); ^b P value 0.0003 (Full term control vs Preeclampsia, IUGR); ^c P value 0.0009 (Full term control vs Preeclampsia); ^d P value 0.0055 (Preeclampsia vs IUGR).

ISSN: 1471-2393