Table 3 Gestational age-specific fetal, neonatal and perinatal death rates and odds ratios comparing mothers ≥35 years vs 20–29 years, singleton births, United States, 2003–2005
From: Does advanced maternal age confer a survival advantage to infants born at early gestation?
Traditional model | Fetuses-at-risk model | |||||||
|---|---|---|---|---|---|---|---|---|
Rate per 1000 total birthsa | Unadjusted odds ratio (95% CI) | Adjusted odds ratio (95% CI) | Rate per 1000 fetuses-at-risk | Unadjusted odds ratio (95% CI) | Adjusted odds ratio (95% CI) | |||
age 20–29 years | age ≥35 years | age 20–29 years | age ≥35 years | |||||
Fetal death | ||||||||
22-33 weeks | 75.6 | 76.4 | 1.01 (0.97- 1.06) | 0.97 (0.91-1.03) | 1.6 | 2.0 | 1.21 (1.16- 1.26) | 1.35 (1.27-1.43) |
34-43 weeks | 1.4 | 2.1 | 1.45 (1.39- 1.51) | 1.66 (1.56-1.76) | 1.4 | 2.1 | 1.45 (1.39- 1.51) | 1.66 (1.56-1.76) |
Total | 3.1 | 4.0 | 1.32 (1.28- 1.36) | 1.48 (1.42-1.55) | 3.1 | 4.0 | 1.32 (1.28- 1.36) | 1.48 (1.42-1.55) |
Neonatal death | ||||||||
22-33 weeks | 72.9 | 67.4 | 0.93 (0.88- 0.97) | 0.93 (0.88-0.98) | 1.5 | 1.6 | 1.11 (1.05- 1.16) | 1.31 (1.24-1.38) |
34-43 weeks | 1.1 | 1.2 | 1.13 (1.07- 1.20) | 1.21 (1.14-1.29) | 1.1 | 1.2 | 1.13 (1.07- 1.19) | 1.21 (1.14-1.29) |
Total | 2.5 | 2.8 | 1.12 (1.08- 1.16) | 1.26 (1.21-1.31) | 2.5 | 2.8 | 1.11 (1.08- 1.15) | 1.26 (1.21-1.31) |
Perinatal death | ||||||||
22-33 weeks | 143.0 | 138.7 | 0.97 (0.93- 1.00) | 0.94 (0.90-0.98) | 3.1 | 3.6 | 1.16 (1.12- 1.20) | 1.33 (1.27-1.38) |
34-43 weeks | 2.5 | 3.3 | 1.31 (1.27- 1.36) | 1.42 (1.37-1.49) | 2.5 | 3.3 | 1.31 (1.27- 1.36) | 1.42 (1.37-1.49) |
Total | 5.6 | 6.8 | 1.23 (1.20- 1.25) | 1.37 (1.33-1.41) | 5.6 | 6.8 | 1.23 (1.20- 1.25) | 1.37 (1.33-1.41) |