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Table 1 Characteristics of the studies and regimens used

From: An integrative review of the side effects related to the use of magnesium sulfate for pre-eclampsia and eclampsia management

Author/year

Country

Regimen

Modification from standard regimen

Study Design

Randomized (Y/N)

PRITCHARD REGIMENS [12]

Alauddin 2011 [20]

India

P

N/A

Prospective cohort

N

Bhattarcharjee 2011 [21]

India

P

N/A

RCT

Y

Pm

4 g loading; 6 g/8 h maintenance

Bhattacharya 2010 [22]

India

P

N/A

Case Control

N

Bhalla 1994 [23]

India

Pm

12 g loading

RCT

Y

Chowdhury 2009 [24]

India

P

N/A

RCT

Y

  

Zm

0.6 g/h maintenance

  

Chissell 1994 [25]

South Africa

P

N/A

RCT

Y

Zm

6 g loading 2 g/h maintenance

Crowther 1990 [26]

Zimbabwe

P

N/A

RCT

Y

Ekele 2005 [27]

Nigeria

P

N/A

Prospective cohort

N

Malapaka 2011 [28]

India

P

N/A

RCT

Y

  

Pm

4 g loading; 2 g/3 h maintenance

  

Mahajan 2009 [29]

India

Pm (A)

10 g loading

Prospective cohort

N

Pm (B)

6 g loading

Manorot 1996 [30]

Thailand

P

N/A

RCT

Y

Z

N/A

Mundle 2011 [31]

India

P

N/A

RCT

Y

  

Z

N/A

  

Shoaib 2009 [32]

Pakistan

P

N/A

Prospective cohort

N

  

Pm

No maintenance dose

  

ZUSPAN REGIMENS [33]

Aali 2007 [34]

Iran

Zm

2 g/h maintenance

Prospective cohort

N

Belfort 2003 [35]

14 countries

Z or Zm

6 g loading; 2 g/h maintenance

RCT

Y

Coetzee 1998 [36]

South Africa

Z

N/A

RCT

Y*

Dayicioglu 2003 [37]

Turkey

Zm

4.5 g loading; 1.8 g/h maintenance

Prospective cohort

N

Deshmukh 1985 [38]

Bangladesh

Z or Zm

1 g/h maintenance for 8 h

Prospective cohort

Y

Dommisse 1988 [39]

South Africa

Z or Zm

2 g/h maintenance

RCT

Y

Phuapradit 1993 [40]

Thailand

Zm

5 g loading

Prospective cohort

N

PRITCHARD OR ZUSPAN

Altman 2002 [9]

33 countries

P or Z

N/A

RCT

Y*

Eclampsia Trial Collaborative Group 1995 [8]

9 countries

P or Z1

N/A

RCT

Y

P or Z2

N/A

RCT

Y

DHAKA REGIMENS [41]

Begum 2001 [41]

Bangladesh

D

N/A

Prospective cohort

N

Shilva 2007 [42]

India

D

N/A

RCT

Y*

  

Dm

12 g loading

  1. P = Pritchard; Z = Zuspan; D = Dhaka. Use of “m” after the regimen indicates a modified regimen.
  2. 1 compared against diazepam; 2 compared against phenytoin.
  3. * blinded.