TY - JOUR AU - Neubert, Jennifer AU - Pfeffer, Maren AU - Borkhardt, Arndt AU - Niehues, Tim AU - Adams, Ortwin AU - Bolten, Mareike AU - Reuter, Stefan AU - Stannigel, Hans AU - Laws, Hans-Juergen PY - 2013 DA - 2013/01/24 TI - Risk adapted transmission prophylaxis to prevent vertical HIV–1 transmission: Effectiveness and safety of an abbreviated regimen of postnatal oral Zidovudine JO - BMC Pregnancy and Childbirth SP - 22 VL - 13 IS - 1 AB - Antiretroviral drugs including zidovudine (ZDV) are effective in reducing HIV mother to child transmission (MTCT), however safety concern remains. The optimal duration of postnatal ZDV has not been established in clinical studies and there is a lack of consensus regarding optimal management. The objective of this study was to investigate the effectiveness and safety of a risk adapted two week course of oral postnatal ZDV as part of a combined intervention to reduce MTCT. SN - 1471-2393 UR - https://doi.org/10.1186/1471-2393-13-22 DO - 10.1186/1471-2393-13-22 ID - Neubert2013 ER -