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Table 2 Basal characteristics of the study participants at the time of spontaneous abortion

From: Screening for autoimmune thyroid disorders after spontaneous abortion is cost-saving and it improves the subsequent pregnancy rate

  Treated with levothyroxine Untreated Controls p-value
  Before SpA Newly after SpA    
n 45 28 38 147  
Age (years) 33 34 32 33 0.314
BMI 22.29 21.94 23.42 21.34 0.698
Family history of thyroid disease 19 (42%) 10 (36%) 14 (37%) 37 (25%) 0.118
Autoimmune pattern in TUS 10 (22%) 23 (82%) 30 (73%) 0 (0%) <0.001
FT4 (pmol/l) 14.75 (11.70-22.20) 14.20 (11.30-20.60) 13.80 (11.00-17.50) 14.40 (11.10-20.20) 0.278
TSH (mIU/l) 1.84 (0.51-7.32) 2.26 (0.89-8.88) 1.91 (0.30-4.52) 1.54 (0.58-3.94) 0.002
TPOAb (kIU/l) 68.00 (15.00-4480.00) 118.00 (33.00-2820.00) 42.50 (22.00-1805.00) 41.00 (0.00-163.00) <0.001
Subclinical hypothyroidism - 8 (28%) 13 (34%) - 0.827
Euthyroid AITD - 20 (71%) 25 (66%) - 0.827
  1. The values are expressed as median (range). SpA: spontaneous abortion; TUS: thyroid ultrasound; FT4, serum concentration of free thyroxin; TSH, serum concentration of thyroid stimulating hormone; TPOAb, serum concentration of antibodies to thyroid peroxidase; AITD, autoimmune thyroid disorders. ANOVA on ranks (except women with family history of thyroid disease and autoimmune pattern in TUS: Chi-square test).