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Table 2 power to detect a specified difference for a fixed sample size

From: CORONIS - International study of caesarean section surgical techniques: the follow-up study

Outcome examples

Event rate in 1st group e.g. single layer closure

Event rate in 2nd group e.g. double layer closure

Absolute risk difference

Power available to detect this difference

For all women (number estimated to be ~7,400)

Involuntary infertility

3%

4.5%

1.5%

92%

Subsequent pregnancy

48%

44%

4%

93%

Dyspareunia

19%

16%

3%

92%

For women who have a subsequent pregnancy (number estimated to be ~5,900)

Uterine rupture or dehiscence

4%

5.9%

1.9%

92%

Preterm birth

10%

7.5%

2.5%

93%