Skip to main content

Table 2 Structural abnormalities for T18 and T13 cohorts

From: The natural history of pregnancies with a diagnosis of Trisomy 18 or Trisomy 13; a retrospective case series

  Trisomy 18 (N = 46) Trisomy 13 (N = 24)
Cardiac   
Ventricular septal defect 16 (35%) 5 (21%)
Transposition of Great Arteries 1 (2%) 2 (8%)
Patent ductus arteriosus 1 (2%) 1 (4%)
Cerebral   
Holoprosencephaly 0 7 (29%)
Cerebral ventriculomegaly 4 (9%) 3 (13%)
Microcephaly 1 (2%) 3 (13%)
Dandy Walker variant 1 (2%) 2 (8%)
Structural   
Cleft lip/palate 4 (9%) 11 (46%)
Talipes/rockerbottom feet 10 (22%) 6 (25%)
Clenched hands 9 (20%) 1 (4%)
Polydactyly 0 5 (21%)
Low set ears 2 (4%) 4 (17%)
Short long bones 4 (9%) 0
Overlapping fingers 3 (7%) 1 (4%)
Micrognathia 3 (7%) 0
Ocular hypotelorism 1 (2%) 2 (8%)
Syndactyly 2 (4%) 0
Clinodactyly 1 (2%) 1 (4%)
Prominent forehead 1 (2%) 1 (4%)
Gastrointestinal   
Small/absent stomach 6 (13%) 2 (8%)
Omphalocele 6 (13%) 0
Echogenic bowel 1 (2%) 3 (13%)
Umbilical herniation 1 (2%) 1 (4%)
Respiratory   
Pleural effusion 4 (9%) 0
Diaphragmatic hernia 4 (9%) 0
Renal   
Enlarged/cystic kidneys 4 (9%) 5 (21%)
  1. Structural abnormalities for T18 and T13 cohorts.