| Miller 2006 | Miller 2010 | Magwali 2012 | Miller 2012 | Maknikar 2012b | |||||
---|---|---|---|---|---|---|---|---|---|---|
 | Control | NASG | Control | NASG | Control | NASG | Control | NASG | Control | NASG |
 | n = 18 | n = 35 | n = 183 | n = 327 | n = 190 | n = 162 | n = 150 | n = 42 | n = 53 | n = 69 |
Demographics | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Age mean (SD) | 25.9 (5.3) | 26.9 (5.8) | 30.1 (6.5) | 30.2 (6.3) | 28.3 (5.8) | 28.0 (6.0) | 26.7 (6.9) | 26.8 (7.0) | Â | Â |
Parity mean (SD) | 2.6 (2.5) | 1.5 (1.8) | 4.8 (3.1) | 4.4 (3.3) | 2.4 (1.8) | 2.4 (1.9) | 2.3 (2.2) | 2.3 (2.0) | Â | Â |
Weeks pregnant a, mean (SD) | 38.4 (3.1) | 39.2 (1.2) | 37.7 (2.8) | 37.1 (3.2) | 36.7 (3.7) | 37.4 (3.4) | 36.3 (2.7) | 36.4 (3.0) | Â | Â |
Definitive diagnosis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Uterine atony | 7 (38.9) | 12 (34.3) | 57 (31.2) | 79 (24.2) | 28 (14.7) | 31 (19.1) | 20 (13.3) | 6 (14.3) | Â | Â |
Complications of abortion | 3 (16.7) | 9 (25.7) | 12 (6.6) | 36 (11.0) | 67 (35.3) | 50 (30.9) | 31 (20.7) | 14 (33.3) | Â | Â |
Placenta previa | 1 (5.6) | 0 (0.0) | 11 (6.0) | 22 (6.7) | 4 (2.1) | 6 (3.7) | 10 (6.7) | 0 (0.0) | Â | Â |
Placental abruption | 2 (11.1) | 0 (0.0) | 19 (10.4) | 49 (15.0) | 13 (6.8) | 13 (8.0) | 6 (4.0) | 2 (4.8) | Â | Â |
Ectopic pregnancy | 0 (0.0) | 9 (25.7) | 17 (9.3) | 26 (8.0) | 14 (7.4) | 2 (1.2) | 4 (2.7) | 5 (11.9) | Â | Â |
Molar pregnancy | 0 (0.0) | 1 (2.9) | 1 (0.6) | 6 (1.8) | 1 (0.5) | 0 (0.0) | 2 (1.3) | 0 (0.0) | Â | Â |
Ruptured uterus | 2 (11.1) | 1 (2.9) | 20 (10.9) | 19 (5.8) | 14 (7.4) | 7 (4.3) | 2 (1.3) | 2 (4.8) | Â | Â |
Placenta accreta | 0 (0.0) | 0 (0.0) | 4 (2.2) | 5 (1.5) | 1 (0.5) | 1 (0.6) | 2 (1.3) | 1 (2.4) | Â | Â |
Lacerations/Genital trauma | 1 (5.6) | 1 (2.9) | 4 (2.2) | 24 (7.3) | 10 (5.3) | 6 (3.7) | 31 (20.7) | 3 (7.1) | Â | Â |
Retained placenta | 0 (0.0) | 1 (2.9) | 38 (20.8) | 56 (17.1) | 37 (19.5) | 44 (27.2) | 39 (26.0) | 9 (21.4) | Â | Â |
Other | 2 (11.1) | 1 (2.9) | 0 (0.0) | 3 (0.9) | 1 (0.5) | 1 (0.6) | 3 (2.0) | 0 (0.0) | Â | Â |
Condition on study entry | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Est. blood loss, median (IQR) | 1500 (750) | 1500 (1150) | 1500 (1000) | 1500 (800) | 1000 (800) | 1000 (500) | 700 (500) | 800 (700) | Â | Â |
Mean arterial pressure < 60 | 17 (94.4) | 30 (93.8) | 181 (98.9) | 321 (98.2) | 188 (99.0) | 158 (97.5) | 150 (100.0) | 42 (100.0) | Â | Â |
Unconscious | 2 (11.1) | 6 (18.2) | 27 (15.1) | 41 (12.9) | 6 (3.2) | 12 (7.4) | 1 (0.7) | 1 (2.4) | 53 (100.0) | 69 (100.0) |
Outcomes | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Blood loss median (IQR) | 555 (700) | 250 (350) | 360 (500) | 55 (175) | 600 (520) | 150 (200) | 480 (480) | 430 (370) | Â | Â |
Mortality | 1 (5.6) | 0 (0.0) | 34 (18.6) | 26 (8.0) | 10 (5.3) | 2 (1.2) | 4 (2.7) | 3 (7.1) | 31 (58.5) | 19 (27.5) |