| Miller 2006 | Miller 2010 | Magwali 2012 | Miller 2012 | Maknikar 2012b | |||||
---|---|---|---|---|---|---|---|---|---|---|
 | Control | NASG | Control | NASG | Control | NASG | Control | NASG | Control | NASG |
 | n = 158 | n = 206 | n = 607 | n = 835 | n = 469 | n = 306 | n = 574 | n = 148 | n = 139 | n = 121 |
Demographics | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Age mean (SD) | 27.3 (6.1) | 27.4 (5.7) | 29.0 (6.4) | 29.3 (6.2) | 28.0 (6.1) | 27.9 (6.3) | 26.7 (6.9) | 26.5 (6.9) | Â | Â |
Parity mean (SD) | 2.2 (2.2) | 1.8 (1.8) | 3.2 (2.8) | 3.3 (2.8) | 2.2 (1.7) | 2.4 (1.9) | 2.3 (2.2) | 2.2 (2.1) | Â | Â |
Weeks pregnanta mean (SD) | 37.9 (2.8) | 38.1 (2.9) | 37.4 (3.2) | 37.6 (3.2) | 36.7 (3.8) | 37.2 (3.5) | 36.3 (2.8) | 36.4 (2.7) | Â | Â |
Definitive diagnosis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Uterine atony | 67 (43.0) | 69 (33.5) | 190 (31.3) | 319 (38.2) | 92 (19.6) | 65 (21.2) | 68 (11.8) | 21 (14.2) | Â | Â |
Complications of abortion | 25 (16.0) | 35 (17.0) | 45 (7.4) | 93 (11.1) | 146 (31.1) | 89 (29.1) | 95 (16.6) | 26 (17.6) | Â | Â |
Placenta previa | 4 (2.6) | 6 (2.9) | 40 (6.6) | 31 (3.7) | 16 (3.4) | 12 (3.9) | 33 (5.8) | 4 (2.7) | Â | Â |
Placental abruption | 4 (2.6) | 11 (5.3) | 79 (13.0) | 98 (11.7) | 45 (9.6) | 30 (9.8) | 36 (6.3) | 8 (5.4) | Â | Â |
Ectopic pregnancy | 9 (5.8) | 19 (9.2) | 95 (15.7) | 85 (10.2) | 26 (5.5) | 9 (2.9) | 20 (3.5) | 7 (4.7) | Â | Â |
Molar pregnancy | 3 (1.9) | 5 (2.4) | 7 (1.2) | 11 (1.3) | 2 (0.4) | 2 (0.7) | 3 (0.5) | 0 (0.0) | Â | Â |
Ruptured uterus | 5 (3.2) | 7 (3.4) | 46 (7.6) | 32 (3.8) | 30 (6.4) | 16 (5.2) | 19 (3.3) | 5 (3.4) | Â | Â |
Placenta accreta | 0 (0.0) | 0 (0.0) | 6 (1.0) | 9 (1.1) | 2 (0.4) | 2 (0.7) | 3 (0.5) | 2 (1.4) | Â | Â |
Lacerations/Genital trauma | 15 (9.6) | 29 (14.1) | 25 (4.1) | 65 (7.8) | 26 (5.5) | 14 (4.6) | 166 (28.9) | 38 (25.7) | Â | Â |
Retained placenta | 9 (5.8) | 12 (5.8) | 71 (11.7) | 83 (9.9) | 82 (17.5) | 64 (20.9) | 127 (22.1) | 36 (24.3) | Â | Â |
Other | 15 (9.6) | 13 (6.3) | 3 (0.5) | 9 (1.1) | 2 (0.4) | 2 (0.7) | 4 (0.7) | 0 (0.0) | Â | Â |
Condition on study entry | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Est. blood loss, median (IQR) | 750 (750) | 975 (750) | 1000 (500) | 1200 (500) | 1000 (850) | 1000 (850) | 700 (500) | 781 (700) | Â | Â |
Mean arterial pressure < 60 | 17 (10.8) | 32 (16.0) | 181 (29.9) | 321 (38.5) | 188 (40.1) | 158 (51.6) | 150 (26.1) | 42 (28.4) | Â | Â |
Unconscious | 2 (1.3) | 7 (3.4) | 27 (4.5) | 41 (5.0) | 6 (1.3) | 12 (3.9) | 1 (0.2) | 1 (0.7) | 14 (10.1) | 10 (8.3) |
Outcomes | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Blood loss, median (IQR) | 500 (450) | 250 (400) | 370 (550) | 50 (175) | 500 (550) | 150 (200) | 480 (450) | 400 (370) | Â | Â |
Mortality | 2 (1.3) | 0 (0.0) | 38 (6.3) | 29 (3.5) | 13 (2.8) | 5 (1.6) | 9 (1.6) | 5 (3.4) | 35 (28.9) | 27 (19.4) |