Wavelet principal component analysis of fetal movement counting data preceding hospital examinations due to decreased fetal movement: a prospective cohort study

Table 3 Multivariable logistic regression models for associations between fetal movement patterns and fetal health

CONSULTATIONS DUE TO DECREASED FETAL MOVEMENT,(n =148) OUTCOME: pathology identified at DFM consultation^a
	Simple regression			Multivariable regression
Continuous explanatory variables	Estimate	p	Estimate	SE	p	95% CI
Wavelet PC scores
PC1: general level	0.096	0.163	0.053	0.038	0.208	-0.02 to 0.13
PC2: spike around day of consultation	-0.159	0.164	-0.166	0.128	0.237	-0.41 to 0.08
PC3: inverted U-shape	0.251	0.149	0.294	0.179	0.143	-0.06 to 0.65
Gestational age on day of consultation (days)	0.015	0.106	0.019	0.010	0.093	-0.00 to 0.04
CONSULTATIONS DUE TO DECREASED FETAL MOVEMENT WITHIN 21 DAYS BEFORE BIRTH, (n=76) OUTCOME: Fetal compromise at DFM consultation ^b
Wavelet PC scores
PC1_21: general level	0.066	0.104	0.062	0.043	0.144	-0.02 to 0.15
PC2_21: spike around day of consultation	- 0.070	0.566	-0.103	0.138	0.455	-0.37 to 0.17
PC3_21: inverted U-shape	0.245	0.177	0.308	0.194	0.113	-0.07 to 0.69
Gestational age on day of consultation (days)	- 0.017	0.260	-0.014	0.016	0.361	-0.05 to 0.02

SE, standard error; CI, confidence interval, PC, principal component; DFM, decreased fetal movement.
^aOutcome (binary dependent) variable = pathology identified at consultation (22/148 events). Analysis included fitting a mixed-effects model to account for multiple consultations within pregnancies. Women in the sample had one (n=127), two (n=9), or three (n=1) DFM-related consultations. Mean gestational age at time of consultation was 250 days (range, 184-292 days; standard deviation, 31 days).
^bOutcome (binary dependent) variable = fetal compromise at time of consultation (27/76 events). No women attended more than one consultation within 21 days before birth. Mean gestational age at time of consultation was 271 days (range, 213-292; standard deviation, 16 days).

ISSN: 1471-2393