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Table 1 Baseline description of 382 women initiating ART during pregnancy, by delay in days from screening to ART initiation

From: Systemic delays in the initiation of antiretroviral therapy during pregnancy do not improve outcomes of HIV-positive mothers: a cohort study

 

Not initiating ART during antenatal period

Total initiating ART during antenatal period

Delay from screening to ART initiation during antenatal period

p-value

   

<14 days

14-20 days

21-27 days

28-34 days

35+ days

 

Number of patients

108

382

54

136

61

66

65

--

Median age (IQR)

26 (23–31)

27 (24–31)

29 (24–32)

27 (24–31)

28 (25–32)

27 (25–31)

27 (25–31)

0.965

Median gestation (IQR)

31 (27–34)

27 (23–31)

32 (28–34)

28 (26–32)

27 (23–30)

24 (20–28)

21 (17–25)

<0.001

  <24 weeks

12 (12)

104 (27)

3 (6)

14 (10)

16 (26)

30 (45)

41 (63)

<0.001

  24-28 weeks

25 (24)

134 (35)

12 (22)

57 (42)

26 (43)

21 (32)

18 (28)

 

  29-32 weeks

33 (31)

94 (25)

19 (35)

40 (29)

14 (23)

15 (23)

6 (9)

 

  >32 weeks

34 (33)

50 (13)

20 (37)

25 (18)

5 (8)

0

0

 

WHO stage:  I

67 (62)

206 (55)

25 (48)

83 (62)

38 (62)

34 (52)

26 (40)

0.003

      II

17 (16)

69 (18)

7 (13)

29 (22)

10 (16)

13 (20)

10 (15)

 

      III

22 (20)

90 (24)

17 (33)

18 (13)

13 (21)

15 (23)

27 (42)

 

      IV

2 (2)

13 (3)

3 (6)

4 (3)

0

4 (6)

2 (3)

 

Median CD4 cell count (IQR) *

120 (65–166)

142 (96–186)

139 (85–187)

143 (96–186)

153 (112–210)

133 (104–170)

134 (94–172)

0.538

  CD4 <100 cells/μl

9 (39)

99 (28)

19 (36)

38 (29)

11 (19)

15 (24)

16 (29)

 

Median HIV Viral load (IQR) *

4.9 (4.6-4.9)

4.3 (3.7-4.8)

4.2 (3.4-4.8)

4.2 (3.8-4.8)

4.4 (3.9-4.9)

4.5 (3.9-4.9)

4.6 (4.1-4.8)

0.211

  >5 log10 copies/mL

3 (15)

55 (15)

9 (17)

17 (13)

8 (14)

13 (21)

8 (15)

 
  1. * For the 108 women not starting ART, CD4 data were available on 23 patients (21%) and viral load data were available on 22 patients (20%); for the 382 women starting ART, CD4 data were available on 357 patients (93%) and viral load data were available on 358 patients (94%).