Table 1 Association ( p -value) of the top four SNP candidates with PE a
SNPb | Minor allele frequency (%) | Fisher’s exactp-value | Chr. | Position | SNP type | Closest gene | Distance to gene (kb) | ||
|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Allelic | Genotypic | ||||||
(n = 177) | (n = 115) | ||||||||
rs1426409 | 22.6 | 31.1 | 2.58 × 10-2 | 3.14 × 10-6 | 4 | 36850339 | Intergenic | KIAA1239 | 72.7 |
rs17686866 | 14.2 | 29.1 | 1.97 × 10-5 | 3.80 × 10-6 | 1 | 215251888 | Intronic | ESRRG | 0 |
rs9831647 | 38.1 | 48.3 | 1.65 × 10-2 | 9.36 × 10-6 | 3 | 8546110 | Intronic | LMCD1 | 0 |
rs10743565 | 24.3 | 42.8 | 5.00 × 10-6 | 1.64 × 10-5 | 12 | 25551846 | Intronic | IFLTD1 | 0 |