UCSC Genome Browser plot of the copy-number deletion at chr19:48.461-48.476 Mb. (A) The vertical black lines indicate the minimum region of overlap across all subjects harboring the deletion. Each red horizontal bar represents the length and breakpoints of a deletion detected in either PE cases or controls. Exact CNV breakpoints are unknown. (B) UCSC Genes located within this region. The asterisk denotes the target region (chr19:48,461,720-48,462,020) of the custom TaqMan copy-number assay. (C) Genomic positions of SNP and structural variation copy-number probes used in the Affymetrix SNP 6.0 microarray.