Pregnancy
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Leg casting
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Deficiency of antithrombin, protein C, or protein S
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Postpartum (defined as 6 weeks after delivery)
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Major surgery (>30 minutes; general or spinal anesthesia)
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Activated protein C resistance/factor V Leiden
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Hormonal contraception (birth control pill, patch or needle)
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Acute medical illness with hospital admission for ≥ 3 days
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Prothrombin gene mutation
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Airplane travel (longer than 6 hours)
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Immobilization ≥ 3 days (in bed except to go to washroom)
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Anticardiolipin antibody positivity
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Active cancer
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Nonspecific inhibitor
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