Skip to main content

Table 6 Sample size required for a range of effect sizes and different hypotheses to be tested

From: A randomized trial to investigate the effects of pre-natal and infant nutritional supplementation on infant immune development in rural Gambia: the ENID trial: Early Nutrition and Immune Development

  (i) Main effects of treatments versus placebo (ii) Comparison of pairs of main effects versus one another (iii) Interactions between pairs of treatments
Effect size (% difference in TI) Full dataset Reduced dataset* Full dataset Reduced dataset* Full dataset Reduced dataset*
5% 847 3388 1694 3388 3388 6776
7.5% 385 1542 771 1542 1542 3084
10% 222 888 444 888 888 1776
  1. * Avoiding interference from irrelevant treatment.